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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Radiation-induced cavernous hemangiomas: case report and literature review.
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Radiation-induced cavernous hemangiomas: case report and literature review.

机译：辐射诱发的海绵状血管瘤：病例报告和文献复习。

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摘要

The case of a 51-year-old man diagnosed with two acquired cavernous hemangiomas 17 years after cranial irradiation for a cerebellar astrocytoma is reported. A review of 84 cases of radiation-induced cavernous hemangiomas found in the literature is presented. In this series the mean age at the time of irradiation (+/- SD) was 10.4 +/- 2.0 years (median = 8 years), while the mean time to cavernous hemangioma diagnosis (+/- SD) was 10.3 +/- 1.9 years (median = 8 years). Time to cavernous hemangioma diagnosis was found to be inversely related to radiation dose. Hemorrhage from radiation-induced cavernous hemangiomas was found in 40.0% of patients, with an incidence of 3.9% per patient year. An inverse trend was identified between radiation dose and symptomatic presentation, cavernous hemangioma hemorrhage or surgical resection. This review of radiation-induced cavernous hemangiomas confirms that both younger patients and those who received a larger dose of radiation are at increased risk of radiation-induced cavernous hemangiomas. Our results suggest that, based on an assessment of CT or MR images, there may be an increased risk of hemorrhage when comparing radiation-induced to congenital cavernous hemangiomas. Increasing radiation doses appear to stabilize these lesions, decreasing the risk of a symptomatic presentation, cavernous hemangioma hemorrhage and surgical intervention.
机译：据报道，一名51岁男子在颅内照射后因小脑星形细胞瘤被诊断出两次获得性海绵状血管瘤。本文对文献中发现的84例放射性辐射引起的海绵状血管瘤进行了回顾。在该系列中，放射线照射的平均年龄（+/- SD）为10.4 +/- 2.0岁（中位数= 8岁），而海绵状血管瘤诊断的平均时间（+/- SD）为10.3 +/- 1.9年（中位数= 8年）。发现海绵状血管瘤的诊断时间与放射剂量成反比。在40.0％的患者中发现了辐射诱发的海绵状血管瘤引起的出血，每患者每年3.9％的发生率。在放射剂量和症状表现，海绵状血管瘤出血或手术切除之间发现了相反的趋势。这项对辐射诱发的海绵状血管瘤的回顾证实，年轻患者和接受较大剂量放射治疗的患者，其辐射诱发的海绵状血管瘤的风险均增加。我们的结果表明，根据对CT或MR图像的评估，在比较辐射诱发性和先天性海绵状血管瘤的出血风险可能会增加。增加放射剂量似乎可以稳定这些病变，降低出现症状，海绵状血管瘤出血和手术干预的风险。

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