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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Common carotid flow velocity is associated with cognition in older adults
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Common carotid flow velocity is associated with cognition in older adults

机译：常见的颈动脉流速与老年人的认知有关

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摘要

Aims: To assess the relationship between carotid flow velocity and cognitive impairment in patients with mild-moderate (<50%) carotid artery disease. Methods: We studied 407 participants with available carotid ultrasound and cognitive measures. We related peak systolic velocity (PSV) and end diastolic velocity (EDV) of internal carotid artery (ICA) and common carotid artery (CCA) and intimal medial thickness (IMT) to Mini Mental State Examination (MMSE), Clock Draw Test (CDT), Activities of Daily Living Scale (ADL)and Montreal Cognitive Assessment (MoCA). Results: EDV of CCA was significantly different in higher and lower MoCA (MMSE) groups. Multiple regression analysis demonstrated that lower EDV was significantly associated with lower MoCA (+0.459 per standard deviation (SD), p<0. 01 for the left; +0.539 per SD, p<0. 01 for the right) and CDT (odds ratio (OR) 0.093, p< 0.05 for the left; OR) 0.120, p<0. 01 for the right) scores. PSV of left CCA (-0.205 per SD, p<0.05) and IMT (+42.536 per SD, p< 0.001) were associated with ADL. PSV of right CCA was associated with MMSE (+0.081 per SD, p<0.001). No significant relationship between ICA flow velocity and cognitive performance was observed. Conclusions: Our preliminary data show that common carotid artery flow velocity was associated with cognitive performance.
机译：目的：评估轻度中度（<50％）颈动脉疾病患者的颈动脉流速与认知障碍之间的关系。方法：我们研究了407位具有颈动脉超声检查和认知指标的参与者。我们将颈内动脉（ICA）和颈总动脉（CCA）和内膜中层厚度（IMT）的收缩期峰值速度（PSV）和舒张末期速度（EDV）与最小精神状态检查（MMSE），时钟抽动测试（CDT）相关联），日常生活量表（ADL）和蒙特利尔认知评估（MoCA）的活动。结果：在较高和较低的MoCA（MMSE）组中，CCA的EDV明显不同。多元回归分析表明，较低的EDV与较低的MoCA显着相关（每个标准偏差（SD）+0.459，左侧p <0.01;每个SD +0.539，右侧p <0.01.01）和CDT（奇数）比率（OR）0.093，左侧为p <0.05; OR）0.120，p <0。得分为01）。左CCA的PSV（每个SD为-0.205，p <0.05）和IMT（每个SD为+ 42.536，p <0.001）与ADL相关。右CCA的PSV与MMSE相关（每个SD + 0.081，p <0.001）。没有观察到ICA流速与认知能力之间的显着关系。结论：我们的初步数据表明，颈总动脉流速与认知能力有关。

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