• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Head tremor in cervical dystonia.
【24h】

Head tremor in cervical dystonia.

机译：颈肌张力障碍的头部震颤。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: To compare the clinical characteristics, natural history, and therapeutic outcome of patients with cervical dystonia (CD) with head tremor (HT+) and without head tremor (HT-). METHODS: We prospectively evaluated 114 consecutive patients of CD over a 9-month period with a detailed questionnaire. Chi-square and t-tests were employed for statistical analysis. RESULTS: Seventy-eight (68.4%) patients had head tremor and 27 of them (34.6%) had tremor as one of the first symptoms. Age at onset of symptoms were similar in HT+ and HT- groups; however there was a higher prevalence in women in the former group (66.7% vs. 41.7%; p=0.01). HT+ patients had more frequent positive family history of essential-like hand/head tremor (21.8% vs. 5.5%; p<0.05), associated neck pain (92.3% vs. 77.8%: p<0.05), and essential-like hand tremor (40% vs. 8.3%; p<0.001). They also appeared to have more frequent history of preceding headeck trauma (14.1% vs. 8.3%), frequent head rotation (88.5% vs. 69.4%) and antecollis (12.8% vs. 5.5%) but less often head tilt (37.2% vs. 47.2%) and gestes antagonistes (60.2% vs. 75%) than the HT- patients; however these differences were not statistically significant. The frequency of prior psychiatric illnesses, the incidence of dystonias in other parts of the body, frequency of retrocollis and shoulder elevation, and spontaneous remission were similar in the two groups. CONCLUSION: Head tremor is common in CD and is more commonly associated with hand tremor and family history of tremor or other movement disorders. This supports a possible genetic association between CD and essential tremor (ET). Linkage studies are required to evaluate the genetic association between CD and ET.
机译：目的：比较伴有头震（HT +）和无头震（HT-）的宫颈肌张力障碍（CD）患者的临床特征，自然病史和治疗结果。方法：我们使用详细的调查表对9个月内连续114例CD患者进行了前瞻性评估。卡方检验和t检验用于统计分析。结果：78例患者（68.4％）患有头部震颤，其中27例（34.6％）患有震颤是最早的症状之一。 HT +和HT-组的症状发作年龄相似。然而，前一组中女性患病率更高（66.7％vs. 41.7％; p = 0.01）。 HT +患者的基本家族性手/头部震颤阳性家族史更为频繁（21.8％vs. 5.5％; p <0.05），相关颈痛（92.3％vs. 77.8％：p <0.05）和本质类手震颤（40％vs. 8.3％; p <0.001）。他们似乎也有更频繁的头部/颈部外伤史（14.1％vs. 8.3％），频繁的头部旋转（88.5％vs. 69.4％）和前泡（12.8％vs. 5.5％），但头部倾斜的频率更低（分别比HT-​​患者高37.2％和47.2％）和妊娠拮抗剂（60.2％比75％）;但是这些差异在统计上并不显着。两组中先前的精神疾病的发生频率，身体其他部位的肌张力障碍的发生率，后突和肩部抬高的频率以及自发缓解在两组中相似。结论：头部震颤在CD中很常见，并且更常见于手部震颤和震颤家族史或其他运动障碍。这支持了CD与原发性震颤（ET）之间可能的遗传关联。需要进行连锁研究以评估CD和ET之间的遗传关联。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号