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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Response to Seshia/Reid Letter to the Editor
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Response to Seshia/Reid Letter to the Editor

机译：回复Seshia / Reid给编辑的信

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摘要

Thank you for the interest in our review article on febrile seizures. We agree that further investigations into febrile seizures are certainly warranted, both clinically and experimentally. As mentioned, the Consequences of Prolonged Febrile Seizures in Childhood or FEBSTAT study is a prospective, multicentre study currently underway in the United States which will address the relationship between prolonged febrile seizures and subsequent mesial temporal sclerosis and mesial temporal lobe epilepsy. While previous prospective studies have been undertaken in this area, they have not confirmed the association between febrile seizures and temporal lobe epilepsy found in retrospective studies. Results to date of the FEBSTAT study have shown that prolonged febrile seizures are often of the intermittent form and may be unrecognized in the emergency department. Future data to come from this study, such as evidence on imaging of injury to mesial temporal structures, and development of subsequent epilepsy, will be key in providing guidelines for evidence-based management.
机译：感谢您对我们有关高热惊厥的评论文章的关注。我们同意在临床和实验上肯定有必要进一步调查高热惊厥。如前所述，儿童期高热惊厥的后果或FEBSTAT研究是一项正在进行的前瞻性，多中心研究，目前正在美国进行，该研究将探讨高热惊厥与继发的颞叶硬性硬化与颞叶颞叶癫痫之间的关系。尽管先前在该领域进行了前瞻性研究，但他们尚未确认回顾性研究中发现的高热惊厥与颞叶癫痫之间的关联。迄今为止，FEBSTAT研究的结果表明，长时间的高热惊厥通常是间歇性发作，在急诊科可能无法识别。这项研究提供的未来数据，例如对颞中部颞叶结构损伤的影像学证据，以及随后癫痫的发展，将成为为循证管理提供指南的关键。

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