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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >An evidence based approach to the first unprovoked seizure.
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An evidence based approach to the first unprovoked seizure.

机译：首次无故发作的基于证据的方法。

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摘要

The objective is to illustrate the creation and structure of a particular type of Evidence Based Care (EBC) summary that has direct clinical relevance, the Critically Appraised Topic (CAT). The process consists of a step-by-step application of the EBC principles to a common neurological problem, i.e., a patient presenting with a first, unprovoked generalized seizure. This includes asking a focused clinical question about prognosis for recurrence and the role of antiepileptic drugs; searching the literature to answer the question; selecting the relevant evidence (a meta-analysis about prognosis and a randomized controlled trial about therapy); appraising the literature for its validity and usefulness; and applying the results to the clinical scenario. The result is a one-page, user friendly CAT whose title states a declarative answer to the clinical question. It also contains a description of the literature search and of the evidence, the clinical bottom lines derived from the evidence, and general comments.
机译：目的是说明具有直接临床相关性的特定类型的循证护理（EBC）摘要的创建和结构，即“关键评估主题（CAT）”。该过程包括将EBC原理逐步应用到常见的神经系统问题，即，患者出现首次无故的全身性癫痫发作。这包括询问有关复发的预后以及抗癫痫药作用的重点临床问题;搜索文献以回答问题;选择相关证据（关于预后的荟萃分析和关于治疗的随机对照试验）;评估文献的有效性和实用性;并将结果应用于临床情况。结果是一页用户友好的CAT，其标题说明了对临床问题的声明性答案。它还包含对文献检索和证据的描述，从证据中得出的临床底线以及一般性评论。

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