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Canadian Association of Neuroscience Review: development and plasticity of the auditory cortex.

机译:加拿大神经科学协会评论:听觉皮层的发育和可塑性。

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摘要

The functions of the cerebral cortex are predominantly established during the critical period of development. One obvious developmental feature is its division into different functional areas that systematically represent different environmental information. This is the result of interactions between intrinsic (genetic) factors and extrinsic (environmental) factors. Following this critical period, the cerebral cortex attains its adult form but it will continue to adapt to environmental changes. Thus, the cerebral cortex is constantly adapting to the environment (plasticity) from its embryonic stages to the last minute of life. This review details important factors that contribute to the development and plasticity of the auditory cortex. The instructive role of thalamocortical innervation, the regulatory role of cholinergic projection of the basal forebrain and the potential role of the corticofugal modulation are presented.
机译:大脑皮层的功能主要在发育的关键时期建立。一个明显的发展特征是将其划分为系统代表不同环境信息的不同功能区域。这是内在(遗传)因素与外在(环境)因素相互作用的结果。在此关键时期之后,大脑皮层达到其成年形态,但它将继续适应环境变化。因此,大脑皮质从胚胎期到生命的最后一刻都在不断适应环境(可塑性)。这篇综述详细介绍了有助于听觉皮层发育和可塑性的重要因素。提出了丘脑皮层神经支配的指导作用,基底前脑的胆碱能投射的调节作用以及皮质铁调节的潜在作用。

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