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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Assessing health-related quality of life in patients with migraine.
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Assessing health-related quality of life in patients with migraine.

机译：评估偏头痛患者的健康相关生活质量。

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摘要

BACKGROUND: The place of health-related quality of life (HRQoL) instruments in clinical research trials and clinical practice as compared to more traditional clinical outcome measures such as headache intensity and frequency is unclear. OBJECTIVES: To review the current status of HRQoL measurement in migraine. METHODS: A literature search was done for HRQoL and migraine. Selected articles dealing with migraine and commonly used HRQoL instruments and HRQoL measures used in recent clinical trials were reviewed. RESULTS: Several general and migraine specific HRQoL instruments can detect changes over time in response to at least major changes in migraine therapy. Both also show a correlation with clinical headache features. However, their sensitivity to detect clinically significant changes over time is not clear. CONCLUSION: The SF-36, a general HRQoL measure and several migraine-specific HRQoL instruments are useful endpoints for migraine clinical trials. Their role in clinical practice is yet to be established.
机译：背景：与诸如头痛强度和频率等更传统的临床结果指标相比，与健康相关的生活质量（HRQoL）仪器在临床研究试验和临床实践中的位置尚不清楚。目的：回顾偏头痛中HRQoL测量的现状。方法：文献检索了HRQoL和偏头痛。审查了有关偏头痛和最近在临床试验中使用的常用HRQoL仪器和HRQoL措施的精选文章。结果：至少针对偏头痛治疗的重大变化，几种通用的偏头痛专用HRQoL仪器可以检测到随时间的变化。两者还显示出与临床头痛特征的相关性。但是，它们检测随时间变化的临床显着变化的敏感性尚不清楚。结论：SF-36，一种一般的HRQoL测量方法和几种偏头痛专用的HRQoL仪器是用于偏头痛临床试验的有用终点。它们在临床实践中的作用尚未确定。

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