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首页> 外文期刊>The international journal of lower extremity wounds >The experimental study of hemodynamic changes and pathological morphology after artery anastomosis
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The experimental study of hemodynamic changes and pathological morphology after artery anastomosis

机译：动脉吻合术后血液动力学变化和病理形态学的实验研究

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The purpose of this article is to dynamically observe hemodynamic and medium-term pathomorphological changes and to investigate the pathophysiological variation at the vascular anastomotic stoma. Eighteen New Zealand white rabbits underwent right common carotid artery in situ anastomosis, and the hemodynamic changes of anastomotic stoma were recorded by color Doppler ultrasonography before surgery and 5 minutes, 1 week, 2 weeks, 3 weeks, 4 weeks, 8 weeks, 12 weeks, and 16 weeks after surgery. Pathological sections of stoma were made and the pathomorphological changes viewed. Artery anastomoses were preformed successfully in 15 rabbits; 4 rabbits suffered postoperative death. It took 1.22 ± 0.77 hours to complete every operation. All the data involved, mean velocity, peak systolic velocity, and resistant index, had no significant differences between preoperative and postoperative follow-up. The obvious differences were found in the diameters of stoma 5 minutes, 1 week, 2 weeks, and 3 weeks after operation (P values were.002,.001,.003, and.008, respectively). The variance of stoma diameters 2 weeks later was also different from those after 1 week, but no other differences were observed during other weeks. The decrease in stoma diameters after anastomosis was clear, with the maximum decrease occurring 2 weeks after the operation, after which the diameters of stoma became stable 16 weeks after the operation. Some collagens around anastomoses could be found by the pathological sections of stoma, which indicated that the deposition of collagen might be related to the decrease in stoma diameter.
机译：本文的目的是动态观察血液动力学和中期病理形态学变化，并研究血管吻合口的病理生理变化。新西兰白兔18只，行右颈总动脉原位吻合术，术前及术后5分钟，1周，2周，3周，4周，8周，12周通过彩色多普勒超声记录吻合口的血流动力学变化。 ，以及术后16周。进行造口的病理切片并观察病理形态学变化。在15只兔子中成功地形成了动脉吻合; 4只兔子术后死亡。完成每个操作需要1.22±0.77小时。涉及的所有数据，平均速度，峰值收缩速度和阻力指数，在术前和术后随访之间无显着差异。术后5分钟，1周，2周和3周的造口直径存在明显差异（P值分别为.002，.001，.003和.008）。 2周后的造口直径变化也与1周后不同，但在其他几周内未观察到其他差异。吻合后造口直径的减小是明显的，最大的减小发生在手术后2周，此后，造口直径在手术后16周变得稳定。吻合口的病理切片可以发现吻合口周围的一些胶原蛋白，表明胶原蛋白的沉积可能与造口直径的减小有关。

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