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首页> 外文期刊>The international journal of developmental biology >Neural crest derivatives in ocular and periocular structures
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Neural crest derivatives in ocular and periocular structures

机译:眼和眼周结构中的神经c衍生物

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摘要

In vertebrates, the eye is an ectodermal compound structure associating neurectodermal and placodal anlagen. In addition, it benefits early on from a mesenchymal ectoderm -derived component, the neural crest. In this respect, the construction of chimeras between quail and chick has been a turning point, instrumental in appraising the contribution of the cephalic neural crest to the development of ocular and periocular structures. Given the variety of crest derivatives underscored in the developing eye,this study illustrates the fascinating ability of this unique structure to finely adapt its differentiation to microenvironmental cues. This analysis of neural crest cell contribution to ocular development emphasizes their paramount role to design the anterior segment of the eye, supply refracting media and contribute to the homeostasy of the anterior optic chamber.
机译:在脊椎动物中,眼睛是将神经胚层和角膜层胶原结合的外胚层复合结构。另外,它从间充质外胚层来源的神经,中受益。在这方面,在鹌鹑和雏鸡之间构建嵌合体已成为一个转折点,有助于评估头颈神经rest对眼和眼周结构发展的贡献。考虑到在发育中的眼睛中会显示出多种波峰衍生物,这项研究说明了这种独特的结构具有令人着迷的能力,可以很好地使其分化适应微环境的提示。对神经rest细胞对眼部发育的贡献的这一分析强调了它们在设计眼前节,提供折射介质和促进前视神经室内平衡方面的最重要作用。

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