首页> 外文期刊>The journal of alternative and complementary medicine: research on paradigm, practice, and policy >A randomized trial of nature scenery and sounds versus urban scenery and sounds to reduce pain in adults undergoing bone marrow aspirate and biopsy.
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A randomized trial of nature scenery and sounds versus urban scenery and sounds to reduce pain in adults undergoing bone marrow aspirate and biopsy.

机译:一项针对自然风光与城市风光的随机试验,旨在减轻接受骨髓穿刺和活检的成年人的痛苦。

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OBJECTIVES: Bone marrow aspiration and biopsy (BMAB) is painful when performed with only local anesthetic. Our objective was to determine whether viewing nature scenes and listening to nature sounds can reduce pain during BMAB. DESIGN: This was a randomized, controlled clinical trial. Adult patients undergoing outpatient BMAB with only local anesthetic were assigned to use either a nature scene with accompanying nature sounds, city scene with city sounds, or standard care. The primary outcome was a visual analog scale (0-10) of pain. Prespecified secondary analyses included categorizing pain as mild and moderate to severe and using multiple logistic regression to adjust for potential confounding variables. RESULTS: One hundred and twenty (120) subjects were enrolled: 44 in the Nature arm, 39 in the City arm, and 37 in the Standard Care arm. The mean pain scores, which were the primary outcome, were not significantly different between the three arms. A higher proportion in the Standard Care arm had moderate-to-severe pain (pain rating >/=4) than in the Nature arm (78.4% versus 60.5%), though this was not statistically significant (p = 0.097). This difference was statistically significant after adjusting for differences in the operators who performed the procedures (odds ratio = 3.71, p = 0.02). CONCLUSIONS: We confirmed earlier findings showing that BMAB is poorly tolerated. While mean pain scores were not significantly different between the study arms, secondary analyses suggest that viewing a nature scene while listening to nature sounds is a safe, inexpensive method that may reduce pain during BMAB. This approach should be considered to alleviate pain during invasive procedures.
机译:目的:仅使用局部麻醉药进行骨髓穿刺活检(BMAB)会很痛苦。我们的目标是确定在BMAB期间查看自然场景和收听自然声音是否可以减轻痛苦。设计:这是一项随机对照临床试验。接受仅使用局部麻醉剂的门诊BMAB的成年患者被指定使用伴有自然声音的自然场景,具有城市声音的城市场景或标准护理。主要结果是疼痛的视觉模拟评分(0-10)。预先指定的次要分析包括将疼痛分为轻度,中度至重度,并使用多元逻辑回归来调整潜在的混杂变量。结果:一百二十(120)名受试者入选:自然界44位,城市界39位,标准护理位37位。平均疼痛评分是主要结果,三组之间无显着差异。与自然疗法组相比,标准护理组的疼痛中度至重度(疼痛等级> / = 4)的比例更高(78.4%对60.5%),尽管这在统计学上没有统计学意义(p = 0.097)。调整执行该操作的操作员之间的差异后,该差异具有统计学意义(比值比= 3.71,p = 0.02)。结论:我们证实了较早的发现,表明BMAB的耐受性差。虽然研究组之间的平均疼痛评分没有显着差异,但是次要分析表明,在聆听自然声音的同时观看自然场景是一种安全,廉价的方法,可以减轻BMAB期间的疼痛。应该考虑采用这种方法来减轻侵入性手术过程中的疼痛。

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