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Predicting the Naturalistic Course of Major Depressive Disorder Using Clinical and Multimodal Neuroimaging Information: A Multivariate Pattern Recognition Study

机译:使用临床和多模态神经影像学信息预测重大抑郁症的自然过程:多元模式识别研究

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摘要

BACKGROUND: A chronic course of major depressive disorder (MDD) is associated with profound alterations in brain volumes and emotional and cognitive processing. However, no neurobiological markers have been identified that prospectively predict MDD course trajectories. This study evaluated the prognostic value of different neuroimaging modalities, clinical characteristics, and their combination to classify MDD course trajectories.
机译:背景:严重抑郁症(MDD)的慢性病程与大脑容量以及情感和认知过程的深刻改变有关。但是,尚未发现可预测MDD病程轨迹的神经生物学标记。这项研究评估了不同的神经影像学方法,临床特征及其组合以对MDD过程轨迹进行分类的预后价值。

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