首页> 外文期刊>The Japanese journal of physiology >Hemodynamics under Hippocampal Functional Hyperemia in Anesthetized Rat: A Greater Contribution of Red Blood Cell Velocity Compared to Its Concentration.
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Hemodynamics under Hippocampal Functional Hyperemia in Anesthetized Rat: A Greater Contribution of Red Blood Cell Velocity Compared to Its Concentration.

机译:麻醉大鼠海马功能性充血的血流动力学:与红血球速度相比,红血球速度更大。

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摘要

It remains controversial which of the two regulators, red blood cell velocity (RBC-V) or concentration (RBC-C), is a main contributor to increasing flow (RBC-F) during functional hyperemia in the rat hippocampus induced by N-methyl-D-aspartate (NMDA). To address this, we monitored these parameters simultaneously under NMDA-infusion via microdialysis in the hippocampus of urethane-anesthetized rats and found a greater elevation in RBC-V than in RBC-C. This suggests that an RBC-V-dependent increase in RBC-F occurs under NMDA-induced functional hyperemia in the hippocampus as well as in the cortex.
机译:红细胞速度(RBC-V)或浓度(RBC-C)这两个调节剂中的哪一个是由N-甲基诱导的大鼠海马功能性充血过程中血流量增加(RBC-F)的主要贡献者,仍存在争议-D-天冬氨酸(NMDA)。为了解决这个问题,我们在通过氨基甲酸乙酯麻醉的大鼠海马体进行微透析的NMDA输注下同时监测了这些参数,发现RBC-V的升高幅度大于RBC-C。这表明,在NMDA诱导的海马和皮质功能性充血下,RBC-F的RBC-V依赖性增加发生。

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