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Adverse effects using combined rate-slowing antihypertensive agents.

机译:联合使用降速降压药的不良反应。

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Case 1: A 65-year-old woman presented to the emergency department with new-onset slurred speech and visual blurriness. She had type 2 diabetes and stage 4 chronic kidney disease. A left forearm ante-cubutal arteriovenous shunt had been placed 3 months prior to admission and recent estimated glomerular filtration rates (eGFRs) had been 15 to 17 mL/min (normal >89 mL/min). For 20 years, the patient had hypertension, and with progression of her renal disease, blood pressure became more difficult to control. Her antihypertensive regimen had consisted of meto-prolol 50 mg twice a day, hydralazine 100 mg twice a day, lisinopril 40 mg daily, furosemide 80 mg twice a day, and amlodipine 10 mg daily. A week prior to admission, with blood pressure 148/68 mm Hg and a heart rate of 62 beats per minute, clonidine 0.1 mg twice a day had been added.
机译:案例1:一名65岁的女性因出现新的口齿不清和视觉模糊而被送往急诊科。她患有2型糖尿病和4期慢性肾脏疾病。入院前3个月放置了左前臂-前臀动静脉分流术,最近估计的肾小球滤过率(eGFR)为15至17 mL / min(正常> 89 mL / min)。 20年来,该患者患有高血压,并且随着其肾脏疾病的进展,血压变得更加难以控制。她的降压方案包括:每天两次两次50毫克的美托洛尔,一天两次两次200毫克的肼屈嗪,每天两次40毫克的赖诺普利,每天两次80克的呋塞米和每天10毫克的氨氯地平。入院前一周,血压为148/68 mm Hg,心律为每分钟62次,每天两次补充可乐定0.1 mg。

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