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Reynolds Risk Score as a Risk Assessment Tool for Cardiovascular Disease After 10Years: Its Strong Relationship With Blood Pressure

机译:雷诺风险评分作为10年后心血管疾病风险评估工具:与血压的密切关系

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Cardiovascular disease (CVD) is the second leading cause of mortality in Japan, and its prevention is an urgent public health issue. Conventional risk factors for CVD include hypertension, diabetes mellitus, dysli-pidemia, and obesity, and smoking is also considered a modifiable risk.Ridker and colleagues presented the Reynolds Risk Score (RRS), designed to predict the cardiovascular risk over the following 10 years in patients without diabetes. As compared with the Framingham Risk Score (FRS), some biochemical variables are also included in the calculation of the RRS, although individuals with diabetes mellitus are not suitable for the application of either of the risk scores.Comparative studies5'6 have revealed the advantages and limitations of risk scores. The development of a risk score for predicting CVD is useful for recommending risk-lowering actions for each individual, such as smoking cessation, regular exercise habit, dietary regulation of calorie, and salt intake. Because the incidence of CVD is related to genetic factors, RRS includes a family history of CVD. It is also speculated that RRS may be related to the metabolic syndrome, because some components are overlapping.
机译:心血管疾病(CVD)是日本第二大死亡原因,其预防是紧迫的公共卫生问题。传统的CVD危险因素包括高血压,糖尿病,高脂血症和肥胖症,吸烟也被认为是可改变的风险.Ridker和同事提出了雷诺风险评分(RRS),旨在预测未来10年的心血管风险没有糖尿病的患者与Framingham风险评分(FRS)相比,RRS的计算中还包括一些生化变量,尽管患有糖尿病的个体不适合使用这两个风险评分。比较研究5'6显示了其优势和风险评分的局限性。预测CVD的风险评分的发展有助于建议每个人降低风险的措施,例如戒烟,规律的运动习惯,饮食中的热量调节和盐分摄入。由于CVD的发生与遗传因素有关,因此RRS包括CVD的家族史。还推测RRS可能与代谢综合征有关,因为某些成分重叠。

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