• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of clinical hypertension. >Impact of 5-year weight change on blood pressure: Results from the weight loss maintenance trial
【24h】

Impact of 5-year weight change on blood pressure: Results from the weight loss maintenance trial

机译：五年体重变化对血压的影响：减肥维持试验的结果

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this secondary analysis of the Weight Loss Maintenance trial, the authors assessed the relationship between blood pressure (BP) change and weight change in overweight and obese adults with hypertension and/or dyslipidemia who were randomized to 1 of 3 weight loss maintenance strategies for 5 years. The participants were grouped (N=741) based on weight change from randomization to 60 months as: (1) weight loss, (2) weight stable, or (3) weight gain. A significant positive correlation between weight change and systolic BP (SBP) change at 12, 30, and 60 months and between weight change and diastolic BP (DBP) change at 30 months was observed. From randomization to 60 months, mean SBP increased to a similar degree for the weight gain group (4.2±standard error=0.6 mm Hg; P<.001) and weight stable group (4.6±1.1 mm Hg; P<.001), but SBP did not rise in the weight loss group (1.0±1.7 mm Hg, P=53). DBP was unchanged for all groups at 60 months. Although aging may have contributed to rise in BP at 60 months, it does not appear to fully account for observed BP changes. These results suggest that continued modest weight loss may be sufficient for long-term BP lowering.
机译：在减肥维持试验的次要分析中，作者评估了超重和肥胖的高血压和/或血脂异常成年人的血压（BP）变化与体重改变之间的关系，这些成年人被随机分配到3种减肥维持策略中的5种年份。根据从随机分组到60个月的体重变化将参与者分组（N = 741），具体表现为：（1）体重减轻，（2）体重稳定或（3）体重增加。在第12、30和60个月时体重变化与收缩压（SBP）变化之间以及在30个月时体重变化与舒张压（DBP）变化之间存在显着正相关。从随机分组到60个月，体重增加组（4.2±标准误差= 0.6 mm Hg; P <.001）和体重稳定组（4.6±1.1 mm Hg; P <.001）的平均SBP升高至相似的程度，但是在减肥组（1.0±1.7 mm Hg，P = 53）中，SBP没有升高。 60个月时所有组的DBP均未改变。尽管衰老可能是导致60个月BP升高的原因，但似乎并不能完全解释观察到的BP变化。这些结果表明持续适度的体重减轻可能足以长期降低血压。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号