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首页> 外文期刊>The journal of clinical hypertension. >Exploring Issues in Difficult-to-Treat Hypertension
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Exploring Issues in Difficult-to-Treat Hypertension

机译：探索难治性高血压的问题

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The past few years have seen a major increase in clinician interest in difficult-to-treat hypertension, sometimes referred to as treatment-resistant hypertension. This interest has been stimulated largely by new opportunities to treat refractory or severe hypertension with more effective strategies. For instance, new drug combinations, including up to three powerful and well-tolerated agents all within a single tablet, have provided a simple solution for many patients who require multiple drugs to control their hypertension. Perhaps the biggest stimulus to discussions of treatment-resistant hypertension, however, has been the recent development of the technique of renal denerva-tion. This method of treating hypertension depends on ablation of the renal nerves produced by applying energy-most usually by radiofrequency-through catheters placed in the renal arteries. But even as this new technology has become available, experts in hypertension are starting to question whether, in fact, we could do an equally effective job in managing difficult hypertension with improved regimens based on pharmaco-logic agents already available.
机译：在过去的几年中，临床医生对难治性高血压（有时称为抗药性高血压）的兴趣大大增加。通过更有效的策略治疗难治性或重度高血压的新机会极大地激发了这种兴趣。例如，新药的组合，包括在单一片剂中最多包含三种强大且耐受良好的药物，为许多需要多种药物来控制其高血压的患者提供了一种简单的解决方案。然而，讨论抗高血压治疗的最大刺激因素可能是肾脏去神经技术的最新发展。这种治疗高血压的方法取决于最通常通过放置在肾动脉中的射频导管施加能量来消融肾神经。但是，即使这项新技术已经可用，高血压专家也开始质疑，事实上，我们是否可以通过基于现有药物的改良方案来在控制困难的高血压方面做同样有效的工作。

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