Relationship Between Left Ventricular Geometry and Soluble ST2 in a Cohort of Hypertensive Patients

OjjiD.B.; OpieL.H.; LecourS.; LacerdaL.; AdeyemiO.; SliwaK.

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Relationship Between Left Ventricular Geometry and Soluble ST2 in a Cohort of Hypertensive Patients

机译：高血压患者队列左心室几何形状与可溶性ST2的关系

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Left ventricular (LV) hypertrophy (LVH) is classified according to geometric pattern into 4 types: concentric hypertrophy, eccentric hypertrophy, concentric remodeling, and normal geometry. Prevalence of death and cardiovascular complications associated with hypertension depend on the geometric pattern. Although soluble ST2 levels, a novel cardiac biomarker of mechanical strain is increased in hypertension, the relationship with hypertensive LV geometric patterns has not been studied. The authors investigated the relationship between soluble ST2 levels and LV geometric patterns in a cohort of hypertensive patients. LVH was considered present when echocardiographic LV mass index exceeded 49.2 g/m2.7 in men and 46.2 g/m2.7 in women. Patients with concentric hypertrophy had higher soluble ST2 levels compared with patients with normal geometry (20.4±8.4 ng/mL vs 14.3±5.4 ng/mL, P.002). Therefore, soluble ST2 level is not only affected by hypertensive LV, but may be a future biomarker in differentiating concentric hypertrophy from normal geometry in hypertension.

机译：左心室肥大（LVH）根据几何图案分为4种类型：同心肥大，偏心肥大，同心重塑和正常几何。与高血压相关的死亡和心血管并发症的患病率取决于几何图形。尽管在高血压中可溶的ST2水平（一种新的机械应变心脏生物标志物）水平增加，但尚未研究与高血压LV几何图案的关系。作者研究了一群高血压患者的可溶性ST2水平与LV几何模式之间的关系。当超声心动图左心室质量指数超过男性49.2 g / m2.7和女性46.2 g / m2.7时，认为存在LVH。同心肥大的患者比正常几何形状的患者具有更高的可溶性ST2水平（20.4±8.4 ng / mL对14.3±5.4 ng / mL，P <.002）。因此，可溶性ST2水平不仅受高血压左室的影响，而且可能成为区分同心肥大和高血压正常几何的未来生物标志物。

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《The journal of clinical hypertension.》 |2013年第12期|共6页
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OjjiD.B.; OpieL.H.; LecourS.; LacerdaL.; AdeyemiO.; SliwaK.;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
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1. Relationship Between Left Ventricular Geometry and Soluble ST2 in a Cohort of Hypertensive Patients [J] . OjjiD.B., OpieL.H., LecourS., The journal of clinical hypertension. . 2013,第12期

机译：高血压患者队列左心室几何形状与可溶性ST2的关系
2. The effect of left ventricular remodelling on soluble ST2 in a cohort of hypertensive subjects [J] . Ojji D. B., Opie L. H., Lecour S., Journal of human hypertension . 2014,第7期

机译：高血压受试者队列中左心室重塑对可溶性ST2的影响
3. New insights into the relationship of left ventricular geometry and left ventricular mass with cardiac function: A population study of hypertensive subjects. [J] . Chahal NS, Lim TK, Jain European Heart Journal: The Journal of the European Society of Cardiology . 2010,第5期

机译：左心室几何形状和左心室质量与心功能关系的新见解：一项高血压受试者的研究。
4. Prediction of the Supraventricular Arrhythmias in Hypertensive Patients with Different Forms of the Left Ventricular Geometry [C] . A. Oreziak, E. Piatkowska-Janko, Z. Lewandowski, Conference on Computers in Cardiology . 2006

机译：不同形式的左心室几何形式的高血压患者中急性心律失常的预测
5. Association of Left Ventricular Ejection Fraction with Mortality and Hospitalization in an Unselected Echocardiographic Cohort of both Ambulatory and Hospitalized Patients [D] . Angaran, Paul. 2019

机译：左心室喷射分数在外国汽车和住院患者的未选择超声心动图群中死亡和住院治疗
6. The Influence of the Left Ventricular Geometry on the Left Atrial Size and Left Ventricular Filling Pressure in Hypertensive Patients as Assessed by Echocardiography [O] . In Jeong Cho, Wook Bum Pyun, Gil Ja Shin 2009

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Relationship Between Left Ventricular Geometry and Soluble ST2 in a Cohort of Hypertensive Patients

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