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首页> 外文期刊>The journal of clinical hypertension. >Impressive Blood Pressure and Heart Rate Response After Percutaneous Renal Denervation in a Woman With Morbid Obesity and Severe Drug-Resistant Hypertension
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Impressive Blood Pressure and Heart Rate Response After Percutaneous Renal Denervation in a Woman With Morbid Obesity and Severe Drug-Resistant Hypertension

机译:病态肥胖和重度抗药性高血压的妇女经皮肾脏去神经后的血压和心率反应令人印象深刻

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摘要

Resistant hypertension is a growing problem in the United States and around the world. Although its pathophysiology is multifactorial and poorly understood, it is invariably associated with increased renal sympathetic activation and central sympathoexcita-tion.Sympathetic nervous system (SNS) regulation is complex and several mechanisms modulate its activity , with accumulating evidence pointing to the kidney as a key contributor. The kidney, through efferent and afferent sympathetic fibers, acts as both a generator and a recipient of sympathetic signals.
机译:抗性高血压在美国和世界范围内是一个日益严重的问题。尽管其病理生理学是多因素的并且尚不为人所知,但它总是与肾脏交感神经激活和中枢交感神经兴奋有关。交感神经系统(SNS)调节很复杂,多种机制调节其活性,有越来越多的证据表明肾脏是关键贡献者。肾脏通过传出和传入的交感神经纤维,既是交感神经信号的产生者又是接受者。

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