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首页> 外文期刊>The journal of clinical hypertension. >'Get thee up, eat and drink: For there is a sound of abundance of rain' [1 Kings 18:41 King James Version]
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'Get thee up, eat and drink: For there is a sound of abundance of rain' [1 Kings 18:41 King James Version]

机译:“起床,吃饭和喝水:因为有大雨的声音” [1 Kings 18:41 King James Version]

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Looking back over 2012, there seemed to be something of a slowdown in the progress of the field of hypertension. No new blockbuster drugs. No JNC report (sigh...). This seems to me, however, much like the quiet on the eve of the storm and several things make me think that there is much excitement ahead, and that the American Society of Hypertension (ASH) will be in the thick of it. What generates such optimism? Like a preacher with an audience for only a brief time, I hope to make 3 points about the call to optimism. The first point to make is that with the completion of the National Institutes of Health/National Heart, Lung, and Blood Institute guideline trio (ATP4, Obesity, and JNC 2013) we are at an interesting intersection of evidence and evidence gaps. Having had the privilege to serve on JNC 2013 (we had to stop calling it JNC 8, it rhymed with too many other things such as "late" and "wait" and "delayed"), we learned to confront the evidence and acknowledge where it is strong, and where it is weak or insufficient. We labored, with the help of evidence people, guidelines people, and a variety of practitioners, to produce not only a set of actionable recommendations, but an identification of needs in our management algorithms. The most pressing need, and a potential trumpet call to our Society, is to define better the systolic blood pressure (BP) goal in the population at greatest risk for target organ damage that is so clearly linked to systolic pressure: those aged 60 years or older. This year welcomes the author into that elite category. The opportunities here are on several fronts. The growth of electronic health records allows the possibility of sharing information on literally millions of hypertensives in the United States. However, although enhancing greatly the epidemiology of hypertension in an era of multiple cardiac risk factor management, it is not a surrogate for the need for thoughtful BP goal intervention trials in the groups where this is still debated (like in those older than 59 years).
机译:回顾2012年,高血压领域的进展似乎有所放缓。没有新的重磅炸弹药物。没有JNC报告(叹气...)。但是,在我看来,这很像风暴前夕的宁静,有几件事使我认为前方还有很多激动,而美国高血压学会(ASH)将会陷入困境。是什么产生了这种乐观?我希望像在短时间内与听众一样传道的人,希望对乐观的呼吁提出三点看法。首先要说明的是,随着美国国立卫生研究院/国家心脏,肺和血液研究所三项指南(ATP4,肥胖症和JNC 2013)的完成,我们正处于有趣的证据和证据鸿沟之间。曾经有幸在JNC 2013上任职(我们不得不停止称其为JNC 8,它与诸如“迟到”,“等待”和“延迟”之类的太多其他事情押韵),我们学会了面对证据并认识到它强,弱或不足的地方。我们在证据人员,指导人员和各种从业人员的帮助下努力工作,不仅提出了一套可行的建议,而且确定了我们管理算法中的需求。最紧迫的需求,也是对我们协会的潜在号角,是要更好地确定目标器官损害最高风险人群中的收缩压目标,该目标与收缩压明显相关:60岁或以上的人群年长一些。今年欢迎作者进入这一精英类别。这里有很多机会。电子病历的增长使得在美国共享数以百万计的高血压信息成为可能。但是,尽管在多重心脏危险因素管理时代大大提高了高血压的流行病学水平,但这并不能代替仍在争论中的人群(如在59岁以上的人群中)需要进行周到的BP目标干预试验。 。

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