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首页> 外文期刊>The journal of clinical hypertension. >Building on the specialist's antihypertensive treatment recommendation: it's just the beginning.
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Building on the specialist's antihypertensive treatment recommendation: it's just the beginning.

机译：基于专家的抗高血压治疗建议：这仅仅是开始。

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摘要

Patients with established cardiovascular disease are a top priority for preventive medicine. Evidence from clinical trials supports the merits of aggressive risk reduction therapies in survivors of an acute event. Improving their cardiovascular risk factor profile prolongs survival, reduces the incidence of recurrent atherosclerotic events, and improves quality of life. Blood pressure (BP) control is an essential component of cardiovascular disease secondary prevention programs; however, many patients are not receiving adequate antihypertensive therapy to meet their BP goal. By building on the specialist's discharge antihypertensive prescription, primary care physicians are ideally positioned to assume responsibility for ensuring BP goals are achieved and maintained over the long term in patients who have survived an acute event. Current hypertension management guidelines define appropriate BP goals and incorporate clear advice on how these goals can be met. BP should be lowered slowly and carefully through lifestyle modifications and pharmacologic therapy. Antihypertensive treatment should be given according to guidelines for primary prevention, although specific antihypertensive classes are indicated for initial use in post-myocardial infarction and post-stroke patients. In many cases, BP goal attainment will require the use of combination therapy with two or more drugs from different classes. With the availability of effective and safe antihypertensive drug therapies, including fixed-dose combinations, a BP goal of <140/90 mm Hg should be achievable in most patients.
机译：患有心血管疾病的患者是预防医学的重中之重。临床试验的证据支持了在急性事件幸存者中积极降低风险的疗法的优点。改善他们的心血管危险因素可延长生存期，降低动脉粥样硬化事件的复发率，并改善生活质量。血压控制是心血管疾病二级预防计划的重要组成部分;但是，许多患者没有接受足够的降压治疗来达到他们的BP目标。通过建立专家的出院抗高血压处方，初级保健医生可以理想地承担起确保急性病幸存的患者长期达到和维持血压目标的责任。当前的高血压管理指南定义了适当的BP目标，并就如何实现这些目标纳入了明确的建议。通过改变生活方式和药物治疗，应缓慢谨慎地降低血压。尽管已针对心肌梗塞后和中风后患者首次使用特定的降压药类别，但应根据一级预防指南给予降压药治疗。在许多情况下，要达到BP目标，就需要结合使用两种或多种不同类别药物的联合疗法。随着有效和安全的降压药物治疗（包括固定剂量组合）的可用性，大多数患者的BP目标应达到<140/90 mm Hg。

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