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Regulation of raft architecture

机译:筏式建筑规范

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摘要

Raft membrane domains are envisioned as lateral assemblies of cholesterol and sphingolipids which adopt a liquid-ordered membrane phase. Our understanding of the raft architecture in cell membranes is developing rapidly. The current view describes raft domains as small and highly dynamic subdomains of cell membranes. The size and stability of raft domains are essential parameters which determine the function of raft domains in cells. Here we discuss how the architecture and stability of raft domains is regulated by oligomerisation of raft components and by modulation of their molecular composition. [References: 49]
机译:筏膜结构域被设想为采用液体有序膜相的胆固醇和鞘脂的侧向组装体。我们对细胞膜中筏结构的理解正在迅速发展。当前观点将筏域描述为细胞膜的小而高度动态的子域。筏域的大小和稳定性是决定细胞中筏域功能的重要参数。在这里,我们讨论了筏域的结构和稳定性如何通过筏组分的低聚和分子组成的调节来调节。 [参考:49]

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