A novel neuritogenic compound, NGA0187

Yuriko Nozawa; Noriyoshi Sakai; Keita Matsumoto; Kazutoshi Mizoue

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A novel neuritogenic compound, NGA0187

机译：新型神经生成化合物NGA0187

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A new neuritogenic compound NGA0187 was isolated from the fermentation broth of Acremonium sp. TF-0356. The structure of NGA0187 was determined by means of spectroscopic analysis and X-ray diffraction. NGA0187 induced significant neurite outgrowth in PC12 cells. However, survival effect of NGA0187 on the primary culture of cerebral cortical neurons was not observed.

机译：从Acremonium sp。的发酵液中分离出新的神经生成化合物NGA0187。 TF-0356。 NGA0187的结构通过光谱分析和X射线衍射确定。 NGA0187诱导PC12细胞中明显的神经突生长。但是，未观察到NGA0187对大脑皮层神经元原代培养的存活作用。

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《The Journal of Antibiotics: An International Journal》 |2002年第7期|共6页
作者
Yuriko Nozawa; Noriyoshi Sakai; Keita Matsumoto; Kazutoshi Mizoue;
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正文语种 eng
中图分类药学;药品;
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A novel neuritogenic compound, NGA0187

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