Absolute Stereostructures of Cell-adhesion Inhibitors,Peribysins A,E,F and G,Produced by a Sea Hare-derived Periconia sp.

Takeshi Yamada; Mitsunobu Doi; Atsuko Miura; Waka Harada; Mika Hiramura; Katsuhiko Minoura; Reiko Tanaka; Atsushi Numata

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Absolute Stereostructures of Cell-adhesion Inhibitors,Peribysins A,E,F and G,Produced by a Sea Hare-derived Periconia sp.

机译：由海兔衍生的Periconia sp。生产的细胞粘附抑制剂，Peribysins A，E，F和G的绝对立体结构。

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Peribysins E~G (1-3) have been isolated from a strain of Periconia byssoides originally separated from the sea hare Aplysia kurodai.Their absolute Stereostructures have been elucidated on the basis of spectroscopic analyses using ID and 2D NMR techniques and some chemical transformations.In addition,the absolute configuration of peribysin A (4),previously undetermined,has been established by conversion to 2 and 3.All these metabolites inhibited the adhesion of human-leukemia HL-60 cells to HUVEC.

机译：Peribysins E〜G（1-3）是从最初从海兔Aplysia kurodai分离出的Periconia byssoides菌株中分离得到的，他们的绝对立体结构已经在使用1D和2D NMR技术的光谱分析和一些化学转化的基础上得到了阐明。此外，通过转换成2和3可以确定以前没有确定的peribbysin A（4）的绝对构型。所有这些代谢产物均抑制人白血病HL-60细胞与HUVEC的粘附。

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《The Journal of Antibiotics: An International Journal》 |2005年第3期|共7页
作者
Takeshi Yamada; Mitsunobu Doi; Atsuko Miura; Waka Harada; Mika Hiramura; Katsuhiko Minoura; Reiko Tanaka; Atsushi Numata;
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正文语种 eng
中图分类药学;
关键词
fungus; peribysins; cell-adhesion inhibitor; Periconia sp.; sea hare;

机译：真菌;peribysins;细胞粘附抑制剂;Periconia sp .;海兔;

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1. Absolute Stereostructures of Cell-adhesion Inhibitors,Peribysins A,E,F and G,Produced by a Sea Hare-derived Periconia sp. [J] . Takeshi Yamada, Mitsunobu Doi, Atsuko Miura, The Journal of Antibiotics: An International Journal . 2005,第3期

机译：由海兔衍生的Periconia sp。生产的细胞粘附抑制剂，Peribysins A，E，F和G的绝对立体结构。
2. Absolute stereostructures of cell-adhesion inhibitors, macrosphelides C, E–G and I, produced by a Periconia species separated from an Aplysia sea hare [J] . Takeshi Yamada Masashi Iritani Mitsunobu Doi Katsuhiko Minoura Tadayoshi Ito and Atsushi Numata Journal of the Chemical Society, Perkin Transactions 1 . 2001,第22期

机译：细胞粘附抑制剂的绝对立体结构，即大花lide类化合物C，EG和I，是由与海兔分离的Periconia菌种产生的
3. Absolute stereostructures of cell-adhesion inhibitors, macrosphelides C, E-G and I, produced by a Periconia species separated from an Aplysia sea hare [J] . Takeshi Yamada, Masashi Iritani, Mitsunobu Doi, Journal of the Chemical Society, Perkin Transactions 1 . 2001,第22期

机译：细胞粘附抑制剂，大stereo类化合物C，E-G和I的绝对立体结构，是由与海兔分离的桃蚜属物种产生的
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5. Lepadins I–K 3-O-(3’-Methylthio)acryloyloxy-decahydroquinoline Esters from a Bahamian Ascidian Didemnum sp. Assignment of Absolute Stereostructures [O] . Sesselja Ómarsdóttir, Xiao Wang, Hong-bing Liu, -1

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6. Absolute Stereostructures of Cell-adhesion Inhibitors, Peribysins A, E, F and G, Produced by a Sea Hare-derived Periconia sp. [O] . Takeshi Yamada, Mitsunobu Doi, Atsuko Miura, 2005

机译：细胞 - 粘附抑制剂，Peribysins A，E，F和G的绝对立体结构由海野兔衍生的Periconia Sp产生。
7. Identification of Producibility Inhibitors in Standard NAVSEA Ship Design Practices. [R] . Wilkins, J. R., Kraine, G. L., LaChance, G. M., 1993

机译：在标准NaVsEa船舶设计实践中识别可生产性抑制剂。

Absolute Stereostructures of Cell-adhesion Inhibitors,Peribysins A,E,F and G,Produced by a Sea Hare-derived Periconia sp.

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