Essramycin: a first triazolopyrimidine antibiotic isolated from nature.

El Gendy MM; Shaaban M; Shaaban KA; El Bondkly AM; Laatsch H

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Essramycin: a first triazolopyrimidine antibiotic isolated from nature.

机译：埃霉素：从自然界中分离出来的第一种三唑并嘧啶抗生素。

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In the course of our screening program for new bio-active compounds, a novel triazolopyrimidine antibiotic, essramycin (1), was obtained from the culture broth of the marine Streptomyces sp., isolate Merv8102. Structure 1 was established by intensive NMR studies and by mass spectra. The compound is antibacterially active with MIC of 2 to 8 microg/ml against Gram-positive and Gram-negative bacteria, while it showed no antifungal activity. The fermentation and isolation, as well as the structure elucidation and biological activity of 1 are described.

机译：在我们筛选新生物活性化合物的程序中，从海洋链霉菌属分离株Merv8102的培养液中获得了一种新的三唑并嘧啶类抗生素essramycin（1）。结构1是通过深入的NMR研究和质谱确定的。该化合物对革兰氏阳性和革兰氏阴性细菌具有抗菌活性，MIC为2至8微克/毫升，而没有显示出抗真菌活性。描述了1的发酵和分离，以及结构的阐明和生物学活性。

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《The Journal of Antibiotics: An International Journal》 |2008年第3期|共9页
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El Gendy MM; Shaaban M; Shaaban KA; El Bondkly AM; Laatsch H;
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正文语种 eng
中图分类药学;
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1. Essramycin: a first triazolopyrimidine antibiotic isolated from nature. [J] . El Gendy MM, Shaaban M, Shaaban KA, The Journal of Antibiotics: An International Journal . 2008,第3期

机译：埃霉素：从自然界中分离出来的第一种三唑并嘧啶抗生素。
2. Essramycin: a first triazolopyrimidine antibiotic isolated from nature. [J] . El Gendy MM, Shaaban M, Shaaban KA, The Journal of Antibiotics: An International Journal . 2008,第3期

机译：Essramycin：从自然中分离的第一个三唑哌啶啶抗生素。
3. Essramycin: a first triazolopyrimidine antibiotic isolated from nature. [J] . El Gendy MM, Shaaban M, Shaaban KA, The Journal of Antibiotics: An International Journal . 2008,第3期

机译：Essramycin：从自然中分离的第一个三唑哌啶啶抗生素。
4. Abundance and Antibiotic Resistance of Escherichia coli O157:H7 Isolated from Hospital Wastewater in the Kathmandu Valley, Nepal [C] . Ocean THAKALI, Sarmila TANDUKAR, Sunayana RAYA, Water and environment technology conference . 2019

机译：从尼泊尔加德满都谷地医院废水中分离出的大肠杆菌O157：H7的丰度和抗药性
5. Relationship Between Antibiotic Resistance and Sanitizer Susceptibility of Escherichia Coli Isolated from Agricultural Water Used in Hawaii [D] . Nguyen, Yen Pham Thuy. 2020

机译：夏威夷农业用水中抗生素抗性与消毒剂易感性的关系
6. Conservation and variation of nucleotide sequences in Escherichia coli strains isolated from nature. [O] . L Harshman, M Riley 1980

机译：从自然界分离的大肠杆菌菌株中核苷酸序列的保守性和变异性。
7. Essramycin: A First Triazolopyrimidine Antibiotic Isolated from Nature† [O] . Mervat M A El-Gendy, Mohamed Shaaban, Khaled A Shaaban, 2008

机译：essramycin：从自然中分离的第一个三唑嘧啶抗生素†

Essramycin: a first triazolopyrimidine antibiotic isolated from nature.

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