首页> 外文期刊>The Journal of Antibiotics: An International Journal >Ascochytatin, a novel bioactive spirodioxynaphthalene metabolite produced by the marine-derived fungus, Ascochyta sp. NGB4.
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Ascochytatin, a novel bioactive spirodioxynaphthalene metabolite produced by the marine-derived fungus, Ascochyta sp. NGB4.

机译:Ascochytatin是一种由海洋真菌Ascochyta sp。生产的新型生物活性螺二氧基萘代谢物。 NGB4。

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摘要

Ascochytatin, a new spirodioxynaphthalene metabolite produced by a marine-derived fungus, was found from a screening program focused on the bacterial two-component regulatory system. The structure of ascochytatin was determined by spectroscopic methods, including NMR and MS. The relative stereochemistry was determined by an X-ray crystallographic analysis, and the absolute stereochemistry was determined by the modified Mosher's method.
机译:从针对细菌两成分调节系统的筛选程序中发现了一种由海洋真菌产生的新型螺二氧基萘代谢产物Ascochytatin。通过包括NMR和MS在内的光谱方法确定了抗壁球蛋白的结构。通过X射线晶体学分析确定相对立体化学,并且通过改进的Mosher法确定绝对立体化学。

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