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Novel macrolactins as antibiotic lactones from a marine bacterium

机译:来自海洋细菌的新型内酯作为抗生素内酯

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Seven new macrolactins (named G-M) and known macrolactins A and F were isolated from a culture broth of Bacillus sp. PP19-H3. The strain had been isolated from the macroalga, Schizymenia dubyi. Macrolactin A, which was 24-membered lactone, had previously been reported to show antibacterial, cytotoxic and antiviral activities. The new macrolactins include 22-membered ring or dicyclic lactone in addition to geometric isomers of known macrolactins A and E The antibacterial activities of all the macrolactins examined in this study were relatively weak. [References: 18]
机译:从芽孢杆菌属(Bacillus sp。)的培养液中分离出七种新的大乳素(命名为G-M)和已知的大乳素A和F。 PP19-H3。该菌株已从巨藻Schizymenia dubyi分离。 Macrolactin A是24元内酯,先前已报道其具有抗菌,细胞毒性和抗病毒活性。除了已知的大内泌素A和E的几何异构体外,新的大内泌素还包括22元环或二环内酯。本研究中检查的所有大内泌素的抗菌活性均相对较弱。 [参考:18]

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