III. Structures of New Hibarimicin-related Metabolites Produced by Blocked Mutants

Yasuhiro Igarashi; Takayuki Kajiura; Tamotsu Furumai; Hiroshi Hori; Kazuaki Higashi; Tadayuki Ishiyama; Masakazu Uramoto; Yoshimasa Uehara; Toshikazu Oki

首页> 外文期刊>The Journal of Antibiotics: An International Journal >III. Structures of New Hibarimicin-related Metabolites Produced by Blocked Mutants

【24h】

III. Structures of New Hibarimicin-related Metabolites Produced by Blocked Mutants

机译：三，封闭突变体产生的与新霉素相关的代谢物的结构

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Structures of metabolites produced by blocked mutants of Microbispora rosea subsp. hibaria TP-A0121, hibarimicin-producer, were determined by spectroscopic analysis. HMP-66 is the dimer of the west half of hibarimicin B, the aglycon of which is the genuine biosynthetic intermediate. HMP-P1 is the shunt product arising from the release of a methanol molecule from hibarimicinone. HMP-P4, the glycoside of HMP-P1, is glycosylated with two amicetoses and two digitoxoses same as hibarimicin B. HMP-M1, M2, M3 and M4 are shunt products derived from the monomeric undecaketide intermediates.

机译：微双孢菌玫瑰亚种的封闭突变体产生的代谢物结构。通过光谱分析确定了hibararia TP-A0121，hibarimicin的生产者。 HMP-66是hibarimicin B西半部分的二聚体，其糖苷配基是真正的生物合成中间体。 HMP-P1是从Hibarimicinone释放出甲醇分子而产生的分流产物。 HMP-P4是HMP-P1的糖苷，与hibarimicin B相同，被两个乙酰氨基糖和两个洋地黄糖糖基化。HMP-M1，M2，M3和M4是衍生自单体去甲蝶呤中间体的分流产物。

著录项

来源
《The Journal of Antibiotics: An International Journal》 |2002年第1期|共10页
作者
Yasuhiro Igarashi; Takayuki Kajiura; Tamotsu Furumai; Hiroshi Hori; Kazuaki Higashi; Tadayuki Ishiyama; Masakazu Uramoto; Yoshimasa Uehara; Toshikazu Oki;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药学;药品;
关键词

相似文献

外文文献
中文文献
专利

1. III. Structures of New Hibarimicin-related Metabolites Produced by Blocked Mutants [J] . Yasuhiro Igarashi, Takayuki Kajiura, Tamotsu Furumai, The Journal of Antibiotics: An International Journal . 2002,第1期

机译：三，封闭突变体产生的与新霉素相关的代谢物的结构
2. Genetic Analysis of Simian Virus 40 III. Characterization of a Temperature-Sensitive Mutant Blocked at an Early Stage of Productive Infection in Monkey Cells [J] . James A. Robb, Robert G. Martin Journal of Virology . 1972,第6期

机译：Simian病毒40 III的遗传分析。在猴细胞的高效性感染早期阻断温度敏感突变体的表征
3. Genetic Analysis of Simian Virus 40 III. Characterization of a Temperature-Sensitive Mutant Blocked at an Early Stage of Productive Infection in Monkey Cells [J] . James A. Robb, Robert G. Martin Journal of Virology . 1972,第6期

机译：Simian病毒40 III的遗传分析。在猴细胞的高效性感染早期阻断温度敏感突变体的表征
4. Fragmentation Techniques to Produce Armor Stone Blocks for Marine Structures - A Case Study [C] . A. Ravi Kumar, Y. Nagendra Annual Conference on Explosives and Blasting Technique vol.1; 20050206-09; Orlando,FL(US) . 2005

机译：碎裂技术生产用于海洋结构的装甲砌块-案例研究
5. Part I. Solvolysis regioselectivity and x-ray structure of the duocarmycin SA alkylation subunit. Part II. Solution phase synthesis of compound libraries targeting the erythropoietin receptor. Part III. Identification of a new class of angiogenesis inhibitors which function by blocking the interaction of proteinase MMP2 and integrin alpha(v)beta(3) [D] . Goldberg, Joel Adam 2000

机译：第一部分：杜卡霉素SA烷基化亚基的溶剂分解区域选择性和X射线结构。第二部分靶向促红细胞生成素受体的化合物库的溶液相合成。第三部分通过阻断蛋白酶MMP2和整联蛋白α（v）beta（3）的相互作用来识别新型血管生成抑制剂
6. Membrane Structures of the Hemifusion-Inducing Fusion Peptide Mutant G1S and the Fusion-Blocking Mutant G1V of Influenza Virus Hemagglutinin Suggest a Mechanism for Pore Opening in Membrane Fusion [O] . Yinling Li, Xing Han, Alex L. Lai, 2005

机译：流感病毒血凝素诱导融合的融合肽突变体G1S和融合封闭突变体G1V的膜结构表明膜融合中的开孔机制。
7. Anthracycline metabolites from baumycin-producing Streptomyces sp. D788. III. New anthracycline metabolites produced by blocked mutants 4L-660 and YDK-18. [O] . AKIHIRO YOSHIMOTO, OSAMU JOHDO, HIROSHI NISHIDA, 1993

机译：产生来自Baumycin的蒽环素代谢物Sp。 D788。 III。通过封闭突变体4L-660和YDK-18产生的新的蒽环素代谢物。
8. The Study of some Stereochemical Problems by X-ray Analysis , The Structure of Ferroverdin, a Nitrosophenol iron (II) Chelate Produced by a Streptomycete. (Thesis submitted for the degree of Doctor of Philosophy at Oxford University). Part III. [R] . S. CANDELORO 1970

机译：通过X射线分析研究一些立体化学问题，Ferroverdin的结构，由链霉菌产生的亚硝基苯酚铁（II）螯合物。（论文提交牛津大学哲学博士学位）。第三部分。

III. Structures of New Hibarimicin-related Metabolites Produced by Blocked Mutants

摘要

著录项

相似文献

相关主题

期刊订阅