New Quinones and Hydroquinones form Malbranchea cinnamomea HKI 286 and HKI 296

Brigitte Schlegel; Frank Hanel; Friedrich A.Gollmick; Hans-Peter Saluz; Udo Grafe

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New Quinones and Hydroquinones form Malbranchea cinnamomea HKI 286 and HKI 296

机译：新的醌和对苯二酚形成Malbranchea cinnamomea HKI 286和HKI 296

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In addition to malbranicin(1) and dihydromalbranicin(5),new substitutd quinones 2,3,6 and hydroquinone 4 were isolated form the culture brotehs of two strains of Malbranchea cinnamome.The chemical constitutions of new metabolites 2,3,4 and 6 were elucidated by optical spectroscopy,mass spectrometry and 1D/2D NMR spectroscopy.2(7-methoxymalbranicin) at a concentration of 42 muM inhibited by 67% Tax/CREB-mediated expression of beta-galactosidase in a recombinant strain of Saccharomyces cerevisiae.

机译：除了Malbranicin（1）和dihydromalbranicin（5）之外，还从两株Malbranchea cinnamome菌株的培养物中分离出了新的取代醌2,3,6和对苯二酚4.新代谢物2,3、4和6的化学组成通过光学光谱，质谱和1D / 2D NMR光谱进行了阐明。2（7-甲氧基青霉素）在重组酿酒酵母中被浓度为67％Tax / CREB介导的β-半乳糖苷酶抑制的42μM浓度。

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《The Journal of Antibiotics: An International Journal》 |2003年第11期|共6页
作者
Brigitte Schlegel; Frank Hanel; Friedrich A.Gollmick; Hans-Peter Saluz; Udo Grafe;
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1. New Quinones and Hydroquinones form Malbranchea cinnamomea HKI 286 and HKI 296 [J] . Brigitte Schlegel, Frank Hanel, Friedrich A.Gollmick, The Journal of Antibiotics: An International Journal . 2003,第11期

机译：新的醌和对苯二酚形成Malbranchea cinnamomea HKI 286和HKI 296
2. LIPOHEXIN, A NEW INHIBITOR OF PROLYL ENDOPEPTIDASE FROM MOESZIA LINDTNERI (HKI-0054) AND PAECILOMYCES SP. (HKI-0055 HKI-0096) .2. INHIBITORY ACTIVITIES AND SPECIFICITY [J] . Christner C., Grafe U., Heinze S., The Journal of Antibiotics: An International Journal . 1997,第5期

机译：脂质体，一种新的抑制剂，来自Moeszia LINDTNERI（HKI-0054）和青霉菌SP的脯氨酸内肽酶。（HKI-0055 HKI-0096）.2。抑制活性和特异性
3. LIPOHEXIN, A NEW INHIBITOR OF PROLYL ENDOPEPTIDASE FROM MOESZIA LINDTNERI (HKI-0054) AND PAECILOMYCES SP. (HKI-0055 HKI-0096) .1. SCREENING, ISOLATION AND STRUCTURE ELUCIDATION [J] . Heinze S., Ihn W., Hulsmann H., The Journal of Antibiotics: An International Journal . 1997,第5期

机译：脂质体，一种新的抑制剂，来自Moeszia LINDTNERI（HKI-0054）和青霉菌SP的脯氨酸内肽酶。（HKI-0055 HKI-0096）.1。筛选，隔离和结构消除
4. Quinone/hydroquinone redox couple as a source of enormous capacitance of activated carbon electrodes [C] . Krzysztof Fic, Mikolaj Meller, Grzegorz Lota, Materials Research Society Symposium on Carbon Nanomaterials . 2013

机译：醌/氢醌氧化还原作为活性碳电极巨大电容的源泉
5. Interactions of the Amyloid-Forming Peptide PAP248-286 with Lipid Membranes: Relating Biophysical Mechanism to Biological Activities [D] . Vane, Eleanor. 2021

机译：淀粉样蛋白肽PAP248-286与脂质膜的相互作用：将生物物理机制与生物活性相关
6. Combination neratinib (HKI-272) and paclitaxel therapy in patients with HER2-positive metastatic breast cancer [O] . L W-C Chow, B Xu, S Gupta, 2013

机译：neratinib（HKI-272）与紫杉醇联合治疗HER2阳性转移性乳腺癌患者
7. Lipohexin, a New Inhibitor of Prolyl Endopeptidase from Moeszia lindtneri (HKI-0054) and Paecilomyces sp. (HKI-0055; HKI-0096). II. Inhibitory Activities and Specificity. [O] . CLAUDIA CHRISTNER, MARION ZERLIN, UDO GRÄFE, 1997

机译：Lipohexin是来自Moeszia Lindtneri（HKI-0054）和佩西胺SP的脯氨酰内肽酶的新抑制剂。（HKI-0055; HKI-0096）。 II。抑制活动和特异性。

New Quinones and Hydroquinones form Malbranchea cinnamomea HKI 286 and HKI 296

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