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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Fungal peritonitis associated with Curvularia geniculata and Pithomyces species in a patient with vulvar cancer who was successfully treated with oral voriconazole
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Fungal peritonitis associated with Curvularia geniculata and Pithomyces species in a patient with vulvar cancer who was successfully treated with oral voriconazole

机译：口服伏立康唑成功治疗的外阴癌患者与霉菌和霉菌相关的真菌性腹膜炎

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摘要

Although fungal peritonitis is uncommon, it occurs most often in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and is associated with significant morbidity and mortality. Candida albicans accounts for the majority of fungal peritonitis episodes. However, rare fungal species have become recognized increasingly as important pathogens for the infection. We report a unique case of fungal peritonitis probably associated with Curvularia geniculata and Pithomyces species developing in a gynecological cancer patient who did not undergo CAPD and was successfully treated with oral voriconazole. A 61-year-old woman with a 5-month history of vulvar cancer, together with diabetes mellitus complicated by a nephropathy, complaining of health problems was admitted to the Gifu University Hospital on 14 August 2001. Immediately after the admission, her vulvar cancer and diabetes were treated with oral medroxyprogester-one acetate and parentheral insulin, respectively. On day 9 during her hospital stay, the patient became febrile and received antibacterial agents, sulbactam/cefoperazone. After 5 days of antibiotic treatment, she complained of lower abdominal pain and tenderness. Examinations at this time revealed the fever level of 37.3 °C, the white blood cell count of 8900 mm -3 and the serum C-reactive protein level of 5.31 gdl-1.
机译：尽管真菌性腹膜炎并不常见，但它最常发生在进行连续非卧床腹膜透析（CAPD）的患者中，并伴有明显的发病率和死亡率。白色念珠菌占真菌性腹膜炎发作的大部分。然而，稀有真菌物种已被越来越多地视为感染的重要病原体。我们报告了一个独特的真菌性腹膜炎病例，该病例可能与一名未接受CAPD且已成功口服伏立康唑治疗的妇科癌症患者中发展的弯曲弧菌和霉菌属有关。一名患有外阴癌5个月病史，患有糖尿病并伴有肾病且患有健康问题的61岁妇女于2001年8月14日入岐阜大学医院住院。入院后不久，她的外阴癌糖尿病和糖尿病分别使用口服甲羟孕酮醋酸盐和肠胃外胰岛素治疗。在住院期间的第9天，患者发热，并接受了舒巴坦/头孢哌酮抗菌剂。经过5天的抗生素治疗，她主诉下腹部疼痛和压痛。此时的检查显示发烧水平为37.3°C，白细胞计数为8900 mm -3，血清C反应蛋白水平为5.31 gdl-1。

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