Inuloxins A-D and derivatives as antileishmanial agents: Structure-activity relationship study

AvolioF.; RimandoA.M.; CimminoA.; AndolfiA.; JainS.; TekwaniB.L.; EvidenteA.

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Inuloxins A-D and derivatives as antileishmanial agents: Structure-activity relationship study

机译：Inuloxins A-D及其衍生物作为抗衰老剂：结构-活性关系研究

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Leishmaniasis, which is manifested in different clinical forms, is a vector-borne disease caused by protozoan parasites belonging to the genus Leishmania. Although a majority of literature mentions only one genus (Lutzomyia) transmitting leishmaniasis to humans in the USA, elsewhere in the world the genus Phlebotomus is considered to be the vector of leishmaniasis. Female sand flies act as carriers of the parasite, and the parasite is transmitted from person to person or from a range of animals to humans.1 In fact, Leishmania species are widespread in 88 countries, affecting the visceral organs, skin and mucous membrane.

机译：利什曼病以不同的临床形式表现，是由利什曼原虫属的原生动物寄生虫引起的媒介传播疾病。尽管大多数文献都提到在美国只有一个属（Lutzomyia）将利什曼病传播给人类，但在世界其他地方，Phlebotomus属被认为是利什曼病的媒介。雌性沙蝇是寄生虫的携带者，该寄生虫在人与人之间或从多种动物到人类之间传播。1实际上，利什曼原虫种类在88个国家中广泛分布，影响内脏器官，皮肤和粘膜。

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《The Journal of Antibiotics: An International Journal》 |2014年第8期|共5页
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AvolioF.; RimandoA.M.; CimminoA.; AndolfiA.; JainS.; TekwaniB.L.; EvidenteA.;
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正文语种 eng
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1. Inuloxins A-D and derivatives as antileishmanial agents: Structure-activity relationship study [J] . AvolioF., RimandoA.M., CimminoA., The Journal of Antibiotics: An International Journal . 2014,第8期

机译：Inuloxins A-D及其衍生物作为抗衰老剂：结构-活性关系研究
2. Synthesis and Structure-Activity Relationships of Lansine Analogues as Antileishmanial Agents [J] . Marco Pieroni, Sisay Girmay, Dianqing Sun ChemMedChem . 2012,第11期

机译：兰辛类似物作为抗leishmanialial剂的合成与构效关系。
3. Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies. [J] . Tasdemir D, Kaiser M, Brun R, Antimicrobial agents and chemotherapy. . 2006,第4期

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6. Synthesis and Structure-Activity Relationships of Lansine Analogs as Antileishmanial Agents [O] . Marco Pieroni, Sisay Girmay, Dianqing Sun, -1

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Inuloxins A-D and derivatives as antileishmanial agents: Structure-activity relationship study

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