Glomosporin, a Novel Antifungal Cyclic Depsipeptide from Glomospora sp. I.Production, Isolation, Physico-chemical Properties and Biological Activities

SATO TSUTOMU; ISHIYAMA DAISUKE; HONDA REIKO; SENDA HISATO; KONNO HIROSHI; TOKUMASU S

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Glomosporin, a Novel Antifungal Cyclic Depsipeptide from Glomospora sp. I.Production, Isolation, Physico-chemical Properties and Biological Activities

机译：Glomosporin，一种来自Glomospora sp。的新型抗真菌环二肽。一，生产，分离，理化性质和生物活性

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A novel antifungal cyclic depsipeptide termed glomosporin, which has a fatty acyl side chain, was isolted from a barley solid culture of Glomospora sp. The strain was isolted from fallen pine leaves collected in Fukusima Prefecture, Japan and identified as Glomospora sp. BAUA 2825.Glomosporin was purified by butanol extraction followed by preparative HPLC. Glomosporin showed antimicrobial activity against fungi including clinically important Aspergillus fumigatus.

机译：从Glomospora sp。的大麦固体培养物中分离出一种新的抗真菌环状二肽肽，称为glomosporin，它具有一个脂肪酰基侧链。从日本福岛县收集的落叶松树中分离出该菌株，并将其鉴定为Glomospora sp。 BAUA 2825.Glomosporin通过丁醇萃取，然后进行制备型HPLC纯化。 Glomosporin对包括临床上重要的烟曲霉在内的真菌显示出抗菌活性。

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《The Journal of Antibiotics: An International Journal》 |2000年第6期|共6页
作者
SATO TSUTOMU; ISHIYAMA DAISUKE; HONDA REIKO; SENDA HISATO; KONNO HIROSHI; TOKUMASU S;
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正文语种 eng
中图分类药学;药品;
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1. Glomosporin, a Novel Antifungal Cyclic Depsipeptide from Glomospora sp. I.Production, Isolation, Physico-chemical Properties and Biological Activities [J] . SATO TSUTOMU, ISHIYAMA DAISUKE, HONDA REIKO, The Journal of Antibiotics: An International Journal . 2000,第6期

机译：Glomosporin，一种来自Glomospora sp。的新型抗真菌环二肽。一，生产，分离，理化性质和生物活性
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5. Chemical studies on antifungal cyclic depsipeptides from an aquatic hyphomycete [D] . Thin Wut Soe, ティン?ウィ?ソ－ 2019

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7. Glomosporin, a Novel Antifungal Cyclic Depsipeptide from Glomospora sp. I. Production, Isolation, Physico-chemical Properties and Biological Activities [O] . Tsutomu Sato, Daisuke Ishiyama, Reiko Honda, 1999

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Glomosporin, a Novel Antifungal Cyclic Depsipeptide from Glomospora sp. I.Production, Isolation, Physico-chemical Properties and Biological Activities

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