CD45 tyrosine phosphatase inhibitory components from Aspergillus niger

Alvi KA.; Rabenstein J.; Davis G.; Baker DD.; Nair BG.

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CD45 tyrosine phosphatase inhibitory components from Aspergillus niger

机译：黑曲霉的CD45酪氨酸磷酸酶抑制成分

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Two inhibitors of CD45 tyrosine phosphatase, dihydrocarolic acid (1) and penitricin D (2), were isolated from a fermentation broth of the fungus Aspergillus niger and purified by HSCCC (high speed countercurrent chromatography) followed by HPLC. The structures were determined by NMR. The inhibitory activities of both compounds were specific to tyrosine phosphatases. [References: 15]

机译：从黑曲霉菌的发酵液中分离出两种CD45酪氨酸磷酸酶抑制剂，二氢叶酸（1）和青霉素D（2），先用HSCCC（高速逆流色谱）纯化，再用HPLC纯化。通过NMR确定结构。两种化合物的抑制活性都对酪氨酸磷酸酶具有特异性。 [参考：15]

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《The Journal of Antibiotics: An International Journal》 |2000年第2期|共4页
作者
Alvi KA.; Rabenstein J.; Davis G.; Baker DD.; Nair BG.;
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正文语种 eng
中图分类药学;药品;
关键词
Receptor; Kinase; Family; Domains;

机译：受体;激酶;家族;域;

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1. CD45 tyrosine phosphatase inhibitory components from Aspergillus niger [J] . Alvi KA., Rabenstein J., Davis G., The Journal of Antibiotics: An International Journal . 2000,第2期

机译：黑曲霉的CD45酪氨酸磷酸酶抑制成分
2. Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase. [J] . M Autero, J Saharinen, T Pessa-Morikawa, Molecular and Cellular Biology . 1994,第2期

机译：p50csk激酶使CD45磷酸酪氨酸磷酸酶的酪氨酸磷酸化产生p56lck酪氨酸激酶的结合位点，并激活磷酸酶。
3. Azaphilones with protein tyrosine phosphatase inhibitory activity isolated from the fungus Aspergillus deflectus [J] . Phytochemistry . 2020,第期

机译：与蛋白质酪氨酸磷酸酶抑制活性的三苯胺从真菌曲霉血小杆菌分离
4. Optimization of Medium components for β-Glucosidase Production from Aspergillus Niger by Response Surface Methodology [C] . Chao ZHANG, Rui HUANG, Hui TIAN, International Conference on Mechanics and Mechatronics . 2013

机译：响应面法从曲霉菌尼日尔β-葡萄糖苷酶生产的培养基组分优化
5. Aspergillus nigerのacid phosphatase生産様式に関する研究 [D] . 島田, 裕司 -1

机译：黑曲霉生产酸性磷酸酶的研究
6. Comparison of the Thermostability Properties of Three Acid Phosphatases from Molds: Aspergillus fumigatus Phytase A. niger Phytase and A. niger pH 2.5 Acid Phosphatase [O] . Markus Wyss, Luis Pasamontes, Roland Rémy, 1998

机译：霉菌中三种酸性磷酸酶的热稳定性能的比较：烟曲霉植酸酶黑曲霉植酸酶和黑曲霉pH 2.5酸性磷酸酶
7. CD45 Tyrosine Phosphatase Inhibitory Components from Aspergillus niger. [O] . KHISAL A. ALVI, BIPIN G. NAIR, JOHN RABENSTEIN, 2000

机译：CD45酪氨酸磷酸酶抑制组分来自曲霉尼日尔。
8. Activation of Tyrosine Phosphorylation in Human T Cells via the CD2 Pathway: Regulation by the CD45 Tyrosine phosphatase. [R] . Samelson, L., Fletcher, M. C., Ledbetter, J. A., 1990

机译：通过CD2途径激活人T细胞中的酪氨酸磷酸化：CD45酪氨酸磷酸酶的调节。

CD45 tyrosine phosphatase inhibitory components from Aspergillus niger

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