Absolute stereochemistry of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1

YamazakiH.; UgakiN.; MatsudaD.; TomodaH.

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Absolute stereochemistry of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1

机译：Penciillium cecidicola FKI-3765-1产生的戊内酯的绝对立体化学，这是小鼠巨噬细胞中脂质滴形成的新抑制剂

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The structure of a new pentacecilide congener, pentacecilide D, produced by Penicillium cecidicola FKI-3765-1 was elucidated by various NMR experiments. The absolute stereochemistry of pentacecilides was elucidated by using the modified Mosher method for pentacecilide C. The inhibitory activity of all pentacecilides against lipid droplet formation and acyl-CoA:cholesterol acyltransferase isozymes was compared.

机译：通过各种NMR实验阐明了由Pedicillium cecidicola FKI-3765-1生产的新的pentacecilide同类物，pentacecilide D的结构。通过使用改良的Mosher方法对五肽杀虫剂C阐明了五肽杀虫剂的绝对立体化学。比较了所有五肽杀虫剂对脂质滴形成和酰基-CoA：胆固醇酰基转移酶同工酶的抑制活性。

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《The Journal of Antibiotics: An International Journal》 |2010年第6期|共4页
作者
YamazakiH.; UgakiN.; MatsudaD.; TomodaH.;
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正文语种 eng
中图分类药学;
关键词
absolute stereochemistry; acyl-CoA:cholesterol acyltransferase; fungal metabolite; lipid droplet formation; Penicillium cecidicola; pentacecilides D;

机译：绝对立体化学;酰基辅酶A：胆固醇酰基转移酶;真菌代谢产物;脂质液滴形成;洋地黄杆菌;戊烯内酯D;

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1. Absolute stereochemistry of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1 [J] . YamazakiH., UgakiN., MatsudaD., The Journal of Antibiotics: An International Journal . 2010,第6期

机译：Penciillium cecidicola FKI-3765-1产生的戊内酯的绝对立体化学，这是小鼠巨噬细胞中脂质滴形成的新抑制剂
2. Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1: I. Taxonomy, fermentation, isolation and biological properties. [J] . Yamazaki H, Kobayashi K, Matsuda D, The Journal of Antibiotics: An International Journal . 2009,第4期

机译：杀青霉菌，小鼠巨噬细胞脂质滴形成的新抑制剂，由青霉菌FKI-3765-1生产：I.分类学，发酵，分离和生物学特性。
3. Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation. [J] . Yamazaki H, Omura S, Tomoda H The Journal of Antibiotics: An International Journal . 2009,第4期

机译：Pentacecilides，新的青霉菌FKI-3765-1产生的小鼠巨噬细胞脂质滴形成抑制剂。结构阐明。
4. Lipid bilayer on a droplet: Formation of lipid bilayers on a droplet array [C] . Tonooka T., Takeuchi S. Micro Electro Mechanical Systems (MEMS), 2012 IEEE 25th International Conference on . 2012

机译：液滴上的脂质双层：在液滴阵列上形成脂质双层
5. An ER-dependent lipid droplet formation model—A subcellular localization study of multiple proteins involved in lipid droplet biogenesis, and, Lipid droplet association of RDH10 and its functional study [D] . Jiang, Weiya 2008

机译：依赖ER的脂质滴形成模型—涉及脂质滴生物发生的多种蛋白质的亚细胞定位研究以及RDH10的脂质滴缔合及其功能研究
6. Rotaviruses Associate with Cellular Lipid Droplet Components To Replicate in Viroplasms, and Compounds Disrupting or Blocking Lipid Droplets Inhibit Viroplasm Formation and Viral Replication [O] . Winsome Cheung, Michael Gill, Alessandro Esposito, 2000

机译：轮状病毒与细胞脂质滴成分相关联以在病毒质中复制，破坏或阻断脂质滴的化合物抑制病毒质形成和病毒复制。
7. Absolute stereochemistry of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1 [O] . Hiroyuki Yamazaki, Narihiro Ugaki, Daisuke Matsuda, 2010

机译：五氯锡，小鼠巨噬细胞脂液滴形成新抑制剂的绝对立体化学，由青霉钙生物钙生物乳钙制成FKI-3765-1
8. Effect of Bone Marrow Depletion on Prostaglandin E-Producing Suppressor Macrophages in Mouse Spleen [R] . Shibata, Y., Volkman, A. 1985

机译：骨髓耗竭对小鼠脾脏前列腺素E抑制巨噬细胞的影响

Absolute stereochemistry of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1

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