...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of Antibiotics: An International Journal >Time-series analysis of the relationship of antimicrobial use and hand hygiene promotion with the incidence of healthcare-associated infections
【24h】

Time-series analysis of the relationship of antimicrobial use and hand hygiene promotion with the incidence of healthcare-associated infections

机译：抗菌药物使用和手部卫生促进与医疗相关感染发生率之间关系的时间序列分析

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We analyzed the effect of antimicrobial use and implementation of a hand hygiene program on the incidence of healthcare-associated infections (HAIs) and healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) infections at the Chung Shan Medical University Hospital (Taichung, Taiwan). Monthly data were retrospectively reviewed from January 2004 to December 2010. Use of antimicrobials and alcohol-based hand cleaner were separately regressed against the incidences of HAIs and HA-MRSA infections. Infection incidence was expressed as persons per 1000 patient days (PDs), monthly use of i.v. antibiotics was expressed as defined daily doses per 1000 PDs and monthly alcohol-based hand cleaner use was expressed as bottle per 1000 PDs. Multivariate analysis indicated that use of hand cleaner was associated with reduced incidence of HAIs (P=0.0001) and HA-MRSA infections (P<0.0001). Time-series analysis indicated that increased use of hand cleaner was significantly associated with significant decreases in the incidences of HAIs and HA-MRSA infections. Total antibiotic use had no significant effect on HAIs, but was associated with more HA-MRSA infections. In addition, the use of J01CR01 antibiotics (combinations of penicillins, including Β-lactamase inhibitors) in particular was correlated with significantly increased incidence of HA-MRSA infections. Our forecasting model demonstrates the efficacy of a hand hygiene program and the need to limit the use of certain restricted antimicrobials in order to reduce the incidence of HAIs and HA-MRSA infections.
机译：我们分析了中山医科大学附属医院（台中市）抗菌药物的使用和手部卫生程序的实施对医疗保健相关感染（HAIs）和与医疗保健相关的耐甲氧西林金黄色葡萄球菌（HA-MRSA）感染发生率的影响台湾）。回顾性地回顾了2004年1月至2010年12月的月度数据。分别针对HAIs和HA-MRSA感染的发生率对抗菌剂和酒精类洗手液的使用情况进行了回归分析。感染发生率表示为每千个患者日（PDs）的人，每月使用i.v.抗生素表示为每1000 PD的每日定义剂量，每月使用酒精的手部清洁剂表示为每1000 PD的瓶子。多变量分析表明，使用洗手液与减少HAIs（P = 0.0001）和HA-MRSA感染（P <0.0001）的发生有关。时间序列分析表明，增加使用洗手液与HAIs和HA-MRSA感染的发生率显着降低显着相关。抗生素的总使用对HAIs没有显着影响，但与更多的HA-MRSA感染有关。此外，使用J01CR01抗生素（青霉素类药物，包括β-内酰胺酶抑制剂）尤其与HA-MRSA感染的发生率显着增加有关。我们的预测模型证明了手部卫生计划的有效性以及限制使用某些限制性抗菌素以减少HAI和HA-MRSA感染的发生的必要性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号