Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1 - I. Taxonomy, production, isolation, physico-chemical properties and biological activities

Momose I.; Kinoshita N.; Iinuma H.; Hamada M.; Takeuchi T.; Chen W.

首页> 外文期刊>The Journal of Antibiotics: An International Journal >Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1 - I. Taxonomy, production, isolation, physico-chemical properties and biological activities

【24h】

Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1 - I. Taxonomy, production, isolation, physico-chemical properties and biological activities

机译：聚酮霉素，一种来自链霉菌属的新抗生素。 MK277-AF1-I.分类学，生产，分离，理化性质和生物活性

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A new antibiotic designated polyketomycin was isolated from the culture broth of Streptomyces sp. MK277-AF1. It was purified by ethyl acetate extraction, Sephadex LH-20 column chromatography and centrifugal partition chromatography (CPC). It inhibited growth of Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA). Its MICs were less than 0.2 mu g/ml. Polyketomycin exhibited cytotoxic activity against nine tumor cell lines at concentrations of 0.9 similar to 5.2 mu g/ml. [References: 10]

机译：从链霉菌属（Streptomyces sp。）的培养液中分离出一种新的名为聚酮霉素的抗生素。 MK277-AF1。通过乙酸乙酯萃取，Sephadex LH-20柱色谱和离心分配色谱法（CPC）对其进行纯化。它抑制包括耐甲氧西林的金黄色葡萄球菌（MRSA）在内的革兰氏阳性细菌的生长。其MIC小于0.2μg/ ml。聚酮霉素在0.9的浓度下（约5.2μg / ml）对九种肿瘤细胞系表现出细胞毒活性。 [参考：10]

著录项

来源
《The Journal of Antibiotics: An International Journal》 |1998年第1期|共5页
作者
Momose I.; Kinoshita N.; Iinuma H.; Hamada M.; Takeuchi T.; Chen W.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药学;药品;
关键词

相似文献

外文文献
中文文献
专利

1. Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1 - I. Taxonomy, production, isolation, physico-chemical properties and biological activities [J] . Momose I., Kinoshita N., Iinuma H., The Journal of Antibiotics: An International Journal . 1998,第1期

机译：聚酮霉素，一种来自链霉菌属的新抗生素。 MK277-AF1-I.分类学，生产，分离，理化性质和生物活性
2. Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391 - I. Taxonomy of producing strain, production, isolation, physico-chemical properties and biological properties [J] . Akiyama T., Kojima F., Takahashi Y., The Journal of Antibiotics: An International Journal . 1998,第6期

机译：Fluostatins A和B是由链霉菌属（Streptomyces sp。）生产的二肽基肽酶III的新抑制剂。 TA-3391-I.生产菌株的分类，生产，分离，理化特性和生物学特性
3. Diperamycin, a new antimicrobial antibiotic produced by Streptomyces griseoaurantiacus MK393-AF2 - I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities [J] . Matsumoto N., Umekita M., Kinoshita N., The Journal of Antibiotics: An International Journal . 1998,第12期

机译：Diperamycin，一种由灰链霉菌MK393-AF2生产的新型抗菌素-I.分类，发酵，分离，理化性质和生物学活性
4. Isolation, identification and activity of insecticidal components from Streptomyces sp. 4138 [C] . B R Lin, X M Pu, H F Shen, International Plant Protection Congress . 2007

机译：杀虫组分的分离，鉴定和活性来自链霉菌SP的杀虫组分。 4138.
5. Studies on nitrogen-containing secondary metabolites from terrestrial and marine origin: Part I. Enzymatic epoxidation of 2,5-dihydroxyacetanilide in Streptomyces sp. Part II. Synthesis of marine sponge alkaloids: Slagenins, axinohydantoins, and studies towards the pyrrolopiperazine system in the agelastatin core. [D] . Barrios Sosa, Ana Carolina. 2002

机译：陆生和海洋来源的含氮次生代谢产物的研究：第一部分。链霉菌属中2,5-二羟基乙酰苯胺的酶促环氧化。第二部分海洋海绵生物碱的合成：Slagenins，Axinohydantoins，以及在astlastatin核心中对吡咯烷哌嗪系统的研究。
6. Cephamycins a New Family of β-Lactam Antibiotics I. Production by Actinomycetes Including Streptomyces lactamdurans sp. n [O] . E. O. Stapley, M. Jackson, S. Hernandez, 1972

机译：头孢菌素β-内酰胺类抗生素的新家族I.放线菌的生产包括内生链霉菌。 ñ
7. Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. [O] . TAKAAKI AOYAGI, TAKAYUKI AOYAMA, FUKIKO KOJIMA, 1992

机译：Benastatins A和B，由Streptomyces SP产生的谷胱甘肽S-转移酶的新抑制剂。 MI384-DF12。 I.分类，生产，分离，物理化学性质和生物活性。

Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1 - I. Taxonomy, production, isolation, physico-chemical properties and biological activities

摘要

著录项

相似文献

相关主题

期刊订阅