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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Obituary: Remembering Emeritus Professor Lester Mitscher (20 August 1931-8 May 2015).
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Obituary: Remembering Emeritus Professor Lester Mitscher (20 August 1931-8 May 2015).

机译：itu告：纪念名誉教授莱斯特·米切尔（1931年8月20日至2015年5月8日）。

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摘要

Approaches to the prevention and management of cardiovascular disease (CVD) are often too narrow in scope and initiated too late. While the majority of adolescents are free of CVD, far fewer are free of CVD risk factors, especially lifestyle factors such as poor exercise and dietary habits. Most clinicians are familiar with behavioral and pharmacologic strategies for modifying these and other traditional CVD risk factors such as hypertension, hypercholesterolemia, and diabetes. In this review, we highlight those strategies most applicable to teens and also propose fundamental reframing that recognizes the importance of early choices and life experiences to achieving cardiovascular health. Population- and individual-level approaches that support the establishment of positive health behaviors early in life are the foundation of preserving ideal cardiovascular health and promoting positive cardiovascular outcomes. The Positive Youth Development movement supports a frame shift away from seeing young people as merely the sum of their risk factors and instead as developmentally dynamic youth capable of making healthy choices. Informed by the Positive Youth Development framework, our approach to cardiovascular prevention among adolescents is both broad based and proactive, paying heed as early as possible to social, familial, and developmental factors that underlie health behaviors and employing evidence-based behavioral, pharmacologic, and surgical treatments when needed.
机译：预防和管理心血管疾病（CVD）的方法范围通常太狭窄，并且启动太晚。尽管大多数青少年没有CVD，但很少有CVD风险因素，尤其是生活方式因素，例如不良运动和饮食习惯。大多数临床医生熟悉改变这些和其他传统CVD危险因素（例如高血压，高胆固醇血症和糖尿病）的行为和药理策略。在这篇综述中，我们重点介绍了最适用于青少年的策略，并提出了基本的构架，以认识到早期选择和生活经验对实现心血管健康的重要性。支持生命早期建立积极健康行为的人群和个人层面的方法，是保持理想的心血管健康和促进积极的心血管结果的基础。积极的青年发展运动支持一个框架转变，不再将年轻人视为其危险因素的总和，而是将他们视为能够做出健康选择的具有发展活力的青年。在积极的青少年发展框架的指导下，我们的青少年心血管预防方法既广泛基础又积极主动，应尽早注意构成健康行为基础的社会，家庭和发育因素，并采用循证的行为，药理学和需要时进行手术治疗。

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