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首页> 外文期刊>The Journal of cardiovascular nursing >Clinical outcomes in metabolic syndrome.
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Clinical outcomes in metabolic syndrome.

机译：代谢综合征的临床结果。

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摘要

Metabolic syndrome is a clustering of cardiovascular risk factors. Its definition is the presence of any 3 of the following: obesity, hypertriglyceridemia, low high-density lipoprotein, hypertension, and impaired fasting glucose. The development of coronary artery disease is the most dreaded complication of this disease. In the United States, Mexican Americans and African American women are the most affected. Management of this syndrome includes physical exercise, weight loss, and effective drug treatment of dyslipidemia, high blood pressure, and impaired fasting blood glucose. Because of the increasing prevalence of obesity and diabetes, there is a rise in fatal and nonfatal cardiovascular events. With the development of effective antiplatelet medication and newer drug-eluting stents, percutaneous coronary intervention has become an effective revascularization strategy for those with coronary artery disease. Rates of stent restenosis and target-lesion revascularization have been reduced. Oral hypoglycemic drugs like thiazolidinediones improve insulin resistance and may have a favorable effect in those with metabolic syndrome. Diagnosis and appropriate management of metabolic syndrome are challenges as the presence of risk factors predates the coronary event.
机译：代谢综合征是心血管危险因素的聚集。它的定义是存在以下任意3种：肥胖，高甘油三酯血症，低密度高脂蛋白，高血压和空腹血糖受损。冠状动脉疾病的发展是该疾病最可怕的并发症。在美国，受影响最严重的是墨西哥裔美国人和非洲裔美国妇女。该综合征的管理包括体育锻炼，体重减轻以及血脂异常，高血压和空腹血糖受损的有效药物治疗。由于肥胖症和糖尿病的患病率增加，致死性和非致死性心血管事件有所增加。随着有效的抗血小板药物和更新的药物洗脱支架的发展，经皮冠状动脉介入治疗已成为患有冠状动脉疾病的人的有效血运重建策略。支架再狭窄和靶病变血运重建率降低。口服降糖药（如噻唑烷二酮）可改善胰岛素抵抗，并可能对代谢综合征患者产生有利影响。代谢综合征的诊断和适当处理面临挑战，因为危险因素的存在早于冠心病。

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