首页> 外文期刊>The Journal of heart and lung transplantation: the official publication of the International Society for Heart Transplantation >Fatal peri-operative hyperacute graft rejection during heart transplantation related to infusion of red blood cell concentrate
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Fatal peri-operative hyperacute graft rejection during heart transplantation related to infusion of red blood cell concentrate

机译:心脏移植过程中致命的围手术期超急性移植排斥反应与输注浓缩红细胞有关

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摘要

With the use of sensitive new technology, hyperacute graft rejection is currently reported as an extremely rare event due to prospective lymphocyte crossmatches and/or virtual crossmatches. In this case study we describe a case of fatal early graft failure after a cardiac transplant in a male recipient who had no anti-HLA antibodies detected before transplantation, but who received, during heart transplant surgery, a red blood cell concentrate containing high levels of graft-specific alloantibodies. In addition, we analyze the relationship between these alloantibodies and the occurrence of hyperacute allograft rejection.
机译:使用敏感的新技术,由于预期的淋巴细胞交叉匹配和/或虚拟交叉匹配,目前报道超急性移植排斥是一种极为罕见的事件。在本案例研究中,我们描述了一个男性接受心脏移植术后致命的早期移植失败的案例,该男性接受者在移植前未检测到抗HLA抗体,但在心脏移植手术期间接受了含有高水平红细胞浓缩物的男性移植物特异性同种抗体。另外,我们分析了这些同种抗体与超急性同种异体移植排斥反应之间的关系。

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