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首页> 外文期刊>The journal of clinical psychiatry >An overview of side effects caused by typical antipsychotics.
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An overview of side effects caused by typical antipsychotics.

机译：典型抗精神病药引起的副作用概述。

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Typical antipsychotics often combine efficacy in treating antipsychotic illnesses with a side effect profile that can affect every system of the body and range from the annoying-photosensitivity and jaundice, for example-to the disabling-seizures and blindness, among others-to the potentially fatal-agranulocytosis and neuroleptic malignant syndrome. The side effects of conventional antipsychotics are associated with effects at CNS transmission and receptor sites and appear in relation to dose levels and potency of the drug. Characteristics of patients-including gender, age, and comorbid medical illness-can make them more or less susceptible to particular antipsychotic side effects. Side effects influence patient quality of life and affect patient compliance with medications. This article will consider the physiologic systems affected by conventional neuroleptics, the sexual and reproductive side effects of typical antipsychotics, and the central nervous side effects of the conventional neuroleptics in the light of these concerns.
机译：典型的抗精神病药通常将治疗抗精神病药的功效与可能会影响身体每个系统的副作用相结合，范围从烦人的光敏性和黄疸，例如致残性癫痫和失明，尤其是可能致命的-粒细胞缺乏症和抗精神病药恶性综合征。常规抗精神病药的副作用与中枢神经系统传播和受体部位的作用有关，并且与药物的剂量水平和效力有关。患者的特征（包括性别，年龄和合并疾病）可以使他们或多或少易受特定的抗精神病药物副作用的影响。副作用影响患者的生活质量，并影响患者对药物的依从性。鉴于这些考虑，本文将考虑受常规抗精神病药影响的生理系统，典型抗精神病药的性和生殖副作用以及常规抗精神病药的中枢神经副作用。

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