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Management of ADHD in adults.

机译:成人多动症的管理。

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Although first identified in children in the 19th century, attention-deficit/hyperactivity disorder (ADHD) in adults was not described in the literature until 1976. The symptoms of adult ADHD resemble the symptoms of childhood ADHD, but symptom intensity, especially hyperactivity, may decrease over time. However, due to the challenges and responsibilities of adulthood, a normal day is extremely complicated for the ADHD adult. Molecular genetics and neuroimaging studies confirm that ADHD is a heterogeneous, neurobiological disorder, mainly of dopaminergic and noradrenergic pathways. Trials of pharmacologic treatments in adults with ADHD have produced mixed results due to considerable variability in diagnostic criteria, dosing, and response. This article reviews the history, neurobiology, and pharmacologic management of adult ADHD.
机译:尽管注意力缺陷多动障碍(ADHD)于19世纪首次在儿童中发现,但直到1976年才在文献中描述了成年人的注意力缺陷/多动障碍。成人ADHD的症状类似于儿童ADHD的症状,但症状强度,尤其是活动过度随时间减少。然而,由于成年的挑战和责任,对于ADHD成年人来说,正常的日子极其复杂。分子遗传学和神经影像学研究证实,ADHD是一种异质性神经生物学疾病,主要是多巴胺能和去甲肾上腺素能途径。由于诊断标准,剂量和反应的巨大差异,成人多动症药物治疗的试验产生了不同的结果。本文回顾了成人多动症的病史,神经生物学和药理学管理。

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