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首页> 外文期刊>The journal of clinical psychiatry >Major depressive disorder and axis I diagnostic comorbidity.
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Major depressive disorder and axis I diagnostic comorbidity.

机译：重度抑郁症和I轴诊断合并症。

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BACKGROUND: Recognition of comorbid conditions in patients presenting for the treatment of depression is clinically important because the presence of other disorders can influence treatment planning. In the present study, we examined the frequency of diagnostic comorbidity in psychiatric outpatients presenting for treatment of nonbipolar major depressive disorder (MDD) and patients' desire for treatment for the comorbid disorders. METHOD: Four hundred seventy-nine psychiatric outpatients with DSM-IV nonbipolar MDD were evaluated with a modified version of the Structured Clinical Interview for DSM-IV. RESULTS: Excluding nicotine dependence, at the time of the evaluation 64.1% (N = 307) of the patients met criteria for at least 1 of the 23 specific Axis I disorders, and more than one third (36.7%, N = 176) had 2 or more disorders. Anxiety disorders, as a group, were the most frequent current comorbid disorders (56.8%), and social phobia was the most frequent individual disorder. Including subthreshold conditions, the percentage of patients with at least 1 disorder increased to 73.5%. When the scope of assessment was expanded to include nicotine dependence, nicotine dependence was the most frequent lifetime individual disorder (38.2%) and the second most frequent current disorder (27.3%). There was considerable variability among the disorders regarding desire for treatment of the comorbid condition. CONCLUSION: The majority of nonbipolar depressed patients have a current comorbid disorder, especially an anxiety disorder, although the actual rate of comorbidity depends on the breadth of the assessment.
机译：背景：在临床上识别抑郁症患者的合并症在临床上很重要，因为其他疾病的存在会影响治疗计划。在本研究中，我们检查了正在治疗非双相性严重抑郁症（MDD）的精神科门诊患者的诊断合并症的频率以及患者对合并症的治疗期望。方法：对479例患有DSM-IV非双相性MDD的精神科门诊患者进行DSM-IV结构化临床访谈的修订版。结果：除尼古丁依赖外，在评估时，有64.1％（N = 307）的患者符合23种特定的I类轴心疾病中至少1种的标准，而超过三分之一（36.7％，N = 176）的患者符合标准2种以上疾病。焦虑症作为一个整体，是当前最常见的合并症（56.8％），社交恐惧症是最常见的个体疾病。包括亚阈值条件，患有至少一种疾病的患者的百分比增加到73.5％。当评估范围扩大到包括尼古丁依赖性时，尼古丁依赖性是一生中最常见的个体疾病（38.2％）和第二高的当前性疾病（27.3％）。在疾病共患病的期望之间存在很大的差异。结论：大多数非双相情感障碍患者患有当前合并症，尤其是焦虑症，尽管合并症的实际发生率取决于评估的广度。

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