首页> 外文期刊>The journal of clinical psychiatry >Ethnic differences in use of antipsychotic medication among Texas medicaid clients with schizophrenia.
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Ethnic differences in use of antipsychotic medication among Texas medicaid clients with schizophrenia.

机译:得克萨斯州精神分裂症患者使用抗精神病药物的种族差异。

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BACKGROUND: Culture and ethnicity have been suggested to influence the presentation of patients with schizophrenia. These factors are thought to affect the diagnoses, courses of treatment, and medical utilization patterns of patients with schizophrenia. Specifically, the differences between whites, African Americans, and Mexican Americans are of particular importance, as these groups comprise the majority of the population in the United States today. The traditional course of treatment for many patients with schizophrenia is the drug haloperidol. However, research has shown that some ethnic groups (African Americans and Mexican Americans) may respond better to atypical drugs, such as olanzapine, but may be less likely to receive these drugs. A better response to the course of treatment results in improved medical utilization patterns. The purpose of this study was to examine if ethnicity helped predict whether Texas Medicaid patients were prescribed haloperidol versus olanzapine when other factors werecontrolled for. METHOD: The study population consisted of 726 patients whose index drug was haloperidol and 1875 patients whose index drug was olanzapine. Patients had an ICD-9-CM diagnosis of schizophrenia or schizoaffective disorder. Texas medical and prescription claims data were used in a logistic regression analysis to determine significant predictors of the type of antipsychotic (haloperidol vs. olanzapine) patients were prescribed. Variables included in the analysis were ethnicity, gender, age, region, other mental illness comorbidities, and previous utilization of medications and resources. Data were collected from Jan. 1, 1996, to Aug. 31, 1998. RESULTS: The results show that when other demographic and utilization factors were controlled for, African Americans were less likely than whites to receive olanzapine rather than haloperidol. CONCLUSION: Ethnicity is a significant predictor of the type of antipsychotic that is prescribed.
机译:背景:文化和种族已被建议影响精神分裂症患者的表现。这些因素被认为会影响精神分裂症患者的诊断,治疗过程和医学利用模式。特别是,白人,非裔美国人和墨西哥裔美国人之间的差异尤为重要,因为这些群体构成了当今美国人口的大部分。许多精神分裂症患者的传统治疗方法是氟哌啶醇。但是,研究表明,某些种族群体(非裔美国人和墨西哥裔美国人)对奥氮平等非典型药物的反应可能更好,但接受这些药物的可能性较小。对治疗过程的更好响应导致改善的医学利用模式。本研究的目的是检验在控制其他因素的情况下,种族是否有助于预测德克萨斯医疗补助患者是否处方氟哌啶醇和奥氮平。方法:研究人群包括726例氟哌啶醇的索引药物和1875例奥氮平的索引药物。患者患有ICD-9-CM诊断为精神分裂症或精神分裂症。在逻辑回归分析中使用了得克萨斯州的医疗和处方索赔数据,以确定处方了抗精神病药(氟哌啶醇与奥氮平)患者类型的重要预测指标。分析中包括的变量是种族,性别,年龄,地区,其他精神疾病合并症以及以前使用的药物和资源。结果收集自1996年1月1日至1998年8月31日。结果:在控制其他人口统计和利用因素的情况下,非洲裔美国人接受奥氮平而不是氟哌啶醇的可能性比白人低。结论:种族是处方抗精神病药的重要预测指标。

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