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首页> 外文期刊>The journal of clinical psychiatry >The impact of attempted suicide on the symptoms and course of mood disorders.
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The impact of attempted suicide on the symptoms and course of mood disorders.

机译：自杀未遂对情绪障碍症状和病程的影响。

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BACKGROUND: Case-controlled studies have produced conflicting results on the relief of depression following attempted suicide. This study examined the impact of attempted suicide on the symptoms and course of mood disorders. METHOD: Of 2800 inpatients reviewed retrospectively, 40 depressed patients who had attempted suicide immediately before admission and 40 depressed but nonsuicidal control patients satisfied entry criteria for the study. The overall severity of their depression had been rated by the treating psychiatrists before the attempted suicide or at admission using the DSM-III-R (or DSM-IV) severity scale. The severity of depression at 1 week after admission was evaluated by reviewing medical records. For categorical analysis, improvement was defined as a reduction of one or more categories on the DSM-III-R (or DSM-IV) severity scale. We assigned scores of 1-6 to this scale to enable quantitative comparisons. RESULTS: Both categorical and dimensional analyses demonstrated that depression was significantly (p <.05) more likely to improve within 1 week of admission among suicidal unipolar patients than among nonsuicidal unipolar patients. Logistic regression analyses revealed that a unipolar course was significantly (p =.023) associated with the improvement of depression. Of the 15 patients showing postsuicidal improvement of depression, 5 (33%) relapsed within 1 month. No significant predictors of their relapses were detected. Of 7 patients with postsuicidal manic switching, 4 (57%) experienced a switch-down into depression. CONCLUSION: This study suggests that unipolar depression is significantly improved after attempted suicide, but also that depressed patients showing postsuicidal improvement or manic switching are likely to undergo relapse or switch-down into depression within a short period.
机译：背景：病例对照研究在自杀未遂后缓解抑郁方面产生了矛盾的结果。这项研究检查了自杀未遂对情绪障碍症状和病程的影响。方法：回顾性回顾了2800名住院患者，其中40例入院前即刻尝试自杀的抑郁症患者和40例抑郁但非自杀性对照患者符合研究的入组标准。自杀未遂之前或入院时，治疗精神病医生已使用DSM-III-R（或DSM-IV）严重性等级对他们的抑郁症总体严重程度进行了评估。入院1周后抑郁的严重程度通过查阅病历进行评估。对于类别分析，改进定义为在DSM-III-R（或DSM-IV）严重性等级上减少一个或多个类别。我们为此评分分配了1-6分，以进行定量比较。结果：分类和维度分析均表明，与非自杀性单极患者相比，自杀性单极患者入院后1周内抑郁症的改善可能性更大（p <.05）。 Logistic回归分析显示，单极病程与抑郁症的改善显着相关（p = .023）。在显示自杀后抑郁改善的15例患者中，有5例（33％）在1个月内复发。没有发现其复发的重要预测指标。在7名自杀后躁狂切换患者中，有4名（57％）经历了抑郁症切换。结论：这项研究表明，自杀未遂后单极抑郁症明显改善，但表现出自杀后改善或躁狂转换的抑郁症患者很可能在短期内复发或转变为抑郁症。

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