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Alcohol abuse and alcoholism: an overview.

机译:酗酒和酗酒:概述。

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摘要

Alcoholism and alcohol abuse rank among the top 3 psychiatric disorders in the United States. These disorders are associated with significant medical and economic consequences. Furthermore, studies consistently show that an investment in addiction treatment leads to overall cost savings for society. Recent work has identified specific effects of alcohol on several neurotransmitter systems, including gamma-aminobutyric acid, serotonin, dopamine, and the opioid receptors. These findings suggest that multiple pharmacologic interventions may be useful for the treatment of alcohol addiction. This article reviews the clinical use of naltrexone and discusses psychosocial programs to enhance treatment retention and adherence.
机译:酗酒和酗酒是美国三大精神疾病之一。这些疾病与重大的医学和经济后果有关。此外,研究始终表明,对成瘾治疗的投资可为社会节省总体成本。最近的工作已经确定了酒精对几种神经递质系统的特定作用,包括γ-氨基丁酸,5-羟色胺,多巴胺和阿片受体。这些发现表明,多种药理干预措施可能对酒精成瘾的治疗有用。本文回顾了纳曲酮的临床使用,并讨论了提高治疗保留率和依从性的社会心理计划。

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