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首页> 外文期刊>The journal of clinical psychiatry >New approaches to managing psychotic depression.
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New approaches to managing psychotic depression.

机译：处理精神病性抑郁症的新方法。

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Major depression with psychotic features, while fairly common, is frequently misdiagnosed. Symptoms seen in these patients are those of an overall severe depressive disorder with psychomotor impairment (retardation or agitation), guilt, suicidal preoccupation, and neuropsychological impairment. A number of biological characteristics and behavioral symptoms are specific to patients suffering from psychotic depression and differ significantly from those of nonpsychotic depression. Psychotic depression is seen in patients of all ages, and it has a high short-term morbidity and risk of suicide. Data support the use of antipsychotics in combination with antidepressants for major depression with psychotic features, but other treatments may have as great or greater efficacy for the disorder. This article focuses on recognizing the features of psychotic depression, the success of current treatment options, and new treatments under investigation.
机译：具有精神病特征的严重抑郁症虽然相当普遍，但经常被误诊。这些患者出现的症状是患有精神运动障碍（迟发或躁动），罪恶感，自杀意识和神经心理障碍的整体严重抑郁症。许多生物学特征和行为症状对于患有精神病性抑郁症的患者是特定的，并且与非精神病性抑郁症的患者明显不同。各个年龄段的患者都可见精神病性抑郁症，其短期发病率高，有自杀的风险。数据支持将抗精神病药与抗抑郁药联合用于具有精神病学特征的重度抑郁症，但其他疗法可能对该病具有同等或更大的疗效。本文着重于认识到精神病性抑郁症的特征，当前治疗方案的成功以及正在研究的新疗法。

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