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首页> 外文期刊>The journal of clinical psychiatry >Prevalence, Correlates, and Comorbidity of Bipolar I Disorder and Axis I and II Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions.
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Prevalence, Correlates, and Comorbidity of Bipolar I Disorder and Axis I and II Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions.

机译：躁郁症I型和I轴和II轴性躁郁症的患病率，相关性和合并症：酒精和相关疾病全国流行病学调查的结果。

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OBJECTIVE: To present nationally representative data on 12-month and lifetime prevalence, correlates, and comorbidity of bipolar I disorder. METHOD: The data were derived from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (N = 43,093). Prevalences and associations of bipolar I disorder with sociodemographic correlates and Axis I and II disorders were determined. RESULTS: Prevalences of 12-month and lifetime DSM-IV bipolar I disorder were 2.0% (95% CI = 1.82 to 2.18) and 3.3% (95% CI = 2.76 to 3.84), respectively, and no sex differences were observed. The odds of bipolar I disorder were significantly greater among Native Americans, younger adults, and respondents who were widowed/separated/divorced and of lower socioeconomic status and significantly lower among Asians and Hispanics (p < .05). Men were significantly (p < .05) more likely to have unipolar mania and earlier onset and longer duration of manic episodes, while women were more likely to have mixed and major depressive episodes and to be treated for manic, mixed, and major depressive episodes. Bipolar I disorder was found to be highly and significantly related (p < .05) to substance use, anxiety, and personality disorders, but not to alcohol abuse. CONCLUSION: Bipolar I disorder is more prevalent in the U.S. population than previously estimated, highlighting the underestimation of the economic costs associated with this illness. Associations between bipolar I disorder and Axis I and II disorders were all significant, underscoring the need for systematic assessment of comorbidity among bipolar I patients.
机译：目的：提供有关双相性I型障碍的12个月和终生患病率，相关性和合并症的全国代表性数据。方法：数据来自2001-2002年全国酒精及相关疾病流行病学调查（N = 43,093）。确定了双相性I型障碍与社会人口统计学相关因素以及Axis I和II型障碍的患病率和关联性。结果：12个月和终生DSM-IV双相I型障碍的患病率分别为2.0％（95％CI = 1.82至2.18）和3.3％（95％CI = 2.76至3.84），未观察到性别差异。在美国原住民，年轻人和丧偶/分居/离婚且社会经济地位较低的受访者中，躁郁症I型患病的几率明显更高，而在亚洲人和西班牙裔中则更低（p <.05）。男性（p <.05）更有可能出现单相躁狂发作，躁狂发作更早且持续时间更长，而女性则更有可能出现混合性和重度抑郁发作，并且需要接受躁狂，混合性和重度抑郁发作的治疗。 。发现双相I障碍与物质使用，焦虑和人格障碍高度相关（p <0.05），但与酗酒无关。结论：躁郁症在美国人口中比以前估计的更为普遍，这突出表明与这种疾病相关的经济成本被低估了。 I型双相情感障碍与Axis I和II型情感障碍之间的关联均很显着，强调需要系统评估I型双相情感障碍患者之间的合并症。

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