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Drs. Mackin and Young Reply

机译:博士Mackin and Young回复

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We thank Dr. Vieweg for his comments regarding our recent article.Dr. Vieweg is correct to state that serum potassium concentration has an important bearing on cardiac repolarization, a fact about which we are well aware. There are also a number of other risk factors for cardiac repolarization abnormalities that have been reviewed elsewhere. Our study was designed specifically to investigate the relationship between QTc prolongation and metabolic parameters, in the absence of any similar data in this patient group. This is an important area of investigation given the reports that patients with severe mental illness are at increased risk of cardiovascular and metabolic disease.
机译:我们感谢Vieweg博士对我们最近的文章发表的评论。 Vieweg正确地指出血清钾浓度与心脏复极有重要关系,对此我们很清楚。对于心脏复极异常,还有许多其他风险因素已在其他地方进行了审查。我们的研究是专门为研究QTc延长与代谢参数之间的关系而设计的,该患者组中没有任何类似数据。有报告指出,患有严重精神疾病的患者罹患心血管疾病和代谢性疾病的风险增加,因此,这是一个重要的研究领域。

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