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首页> 外文期刊>The journal of clinical psychiatry >Psychiatric comorbidity in binge-eating disorder as a function of smoking history.
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Psychiatric comorbidity in binge-eating disorder as a function of smoking history.

机译：暴饮暴食症中的精神病合并症与吸烟史的关系。

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OBJECTIVE: To examine the comorbidity of psychiatric disorders in obese women with binge-eating disorder (BED) as a function of smoking history. METHOD: A consecutive series of 103 obese treatment-seeking women with current DSM-IV diagnoses of BED were administered structured diagnostic interviews to assess all DSM-IV Axis I psychiatric disorders. Participants were classified as "never" or "daily" smokers, and lifetime rates of comorbid psychopathology were compared across smoking groups using logistic regression. The study was conducted from February 2003 to March 2005. RESULTS: Smokers were significantly more likely to meet criteria for co-occurring diagnoses of major depressive disorder (p = .03), panic disorder (p = .01), posttraumatic stress disorder (p < .05), and substance abuse or dependence (p = .01). Even after excluding participants with substance use disorders, significant differences remained, with lifetime smokers having significantly higher rates of co-occurring anxiety disorders. CONCLUSIONS: It is possible that for some obese women with BED, binge eating and cigarette smoking share common functions, i.e., both behaviors may serve to modulate negative affect and/or anxiety. Although the current findings are consistent with a view of a common diathesis for the development of impulsive eating, cigarette or other substance use, and additional Axis I psychopathology, prospective longitudinal studies are needed to elucidate the nature of potential pathways.
机译：目的：探讨肥胖与暴食症（BED）妇女的精神病合并症与吸烟史的关系。方法：对连续103例肥胖，正在接受DSM-IV诊断为BED的肥胖寻求治疗的妇女进行结构化诊断性访谈，以评估所有DSM-IV Axis I精神疾病。参与者被分类为“从不”或“每天”吸烟者，并使用逻辑回归比较了各吸烟组共病的心理病理学终生率。该研究于2003年2月至2005年3月进行。结果：吸烟者符合重症抑郁症（p = .03），恐慌症（p = .01），创伤后应激障碍（ p <.05）和药物滥用或依赖（p = .01）。即使在排除患有药物滥用疾病的参与者之后，仍然存在显着差异，终生吸烟者的同时发生焦虑症的比率明显更高。结论：对于某些患有BED的肥胖女性来说，暴饮暴食和吸烟可能具有共同的功能，即，这两种行为都可能起到调节负面影响和/或焦虑的作用。尽管当前的发现与冲动性饮食，吸烟或其他物质使用发展的普遍素质以及其他的I类心理病理学观点相吻合，但仍需进行前瞻性纵向研究以阐明潜在途径的性质。

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