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首页> 外文期刊>The journal of clinical psychiatry >Clinical differences between suicidal and nonsuicidal depressed children and adolescents.
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Clinical differences between suicidal and nonsuicidal depressed children and adolescents.

机译：自杀和非自杀抑郁儿童和青少年之间的临床差异。

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OBJECTIVE: To examine the clinical symptoms and comorbid psychiatric disorders of depressed children and adolescents with and without clinically significant suicidal ideation. METHOD: Children and adolescents aged 7 to 17 years with current DSM-III-R major depressive disorder (MDD) (N = 135) were recruited between January 1987 and April 2002. Current MDD symptoms and lifetime comorbid psychiatric disorders were assessed using either a combination of the Schedule for Affective Disorders and Schizophrenia for School Age Children-Epidemiologic and -Present Episode versions or the -Present Lifetime version. Thirty-two percent (N = 43) of the depressed subjects were classified as suicidal (at least suicidal ideation with a plan). RESULTS: Depressed suicidal youth presented with a more severe episode (p = .001) and a poorer functional status (p = .019), were more hopeless (p = .001), and presented more frequently with insomnia (p = .011). There was an interaction between suicide x sex x pubertal status for severity of MDD (p = .013), the presence of hopelessness (p < .001), poor functional status (p = .023), and comorbidity with a lifetime history of any disruptive behavior (p = .019). Among pre-pubertal depressed males, suicidal boys had significantly increased severity of MDD (p = .025) and poorer functional status (p = .044) than non-suicidal boys. Among postpubertal depressed females, suicidal girls were more frequently hopeless (p = .008) and presented an increased severity of MDD (p = .022) and more frequent lifetime history of any disruptive behavior (p = .03) when compared with nonsuicidal girls. CONCLUSION: There appears to be a sex difference for some clinical features, particularly hopelessness, among depressed suicidal children and adolescents. Whether hopelessness is a sex-specific characteristic of depressed suicidal children and adolescents requires further study.
机译：目的：探讨抑郁症儿童和青少年是否有明显的自杀意念的临床症状和合并精神疾病。方法：1987年1月至2002年4月，招募了7至17岁患有当前DSM-III-R重度抑郁症（MDD）（N = 135）的儿童和青少年。采用两种方法之一评估当前的MDD症状和终生合并症学龄儿童的情感障碍和精神分裂症时间表的组合-流行病学和-当前情节版本或-当前终生版本。有32％（N = 43）的抑郁者被归类为自杀（至少有计划的自杀念头）。结果：抑郁的自杀青年表现出更严重的发作（p = .001）和较差的功能状态（p = .019），更没有希望（p = .001），并且出现失眠的频率更高（p = .011） ）。自杀x性别x青春期状态与MDD的严重程度（p = .013），绝望的存在（p <.001），不良的功能状态（p = .023）和合并症的终生病史之间存在相互作用。任何破坏性行为（p = .019）。在青春期前的抑郁男性中，自杀男孩比非自杀男孩的MDD严重程度显着增加（p = .025），功能状态较差（p = .044）。与未自杀的女孩相比，在青春期后抑郁的女性中，自杀的女孩更无希望（p = .008），MDD严重程度增加（p = .022），并且有任何破坏性行为的生活史（p = .03）。 。结论：抑郁的自杀儿童和青少年在某些临床特征，特别是绝望方面似乎存在性别差异。无望是否是抑郁的自杀儿童和青少年的性别特征需要进一步研究。

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