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首页> 外文期刊>The journal of clinical psychiatry >Do comorbid personality disorders moderate panic-focused psychotherapy? An exploratory examination of the American Psychiatric Association practice guideline.
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Do comorbid personality disorders moderate panic-focused psychotherapy? An exploratory examination of the American Psychiatric Association practice guideline.

机译：共病的人格障碍是否能缓解以恐慌为中心的心理治疗？美国精神病学协会实践指南的探索性检查。

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OBJECTIVE: The American Psychiatric Association (APA) practice guideline for panic disorder recommends psychodynamic psychotherapy for panic disorder patients with comorbid personality disorders. No data underlie this recommendation. This exploratory study assessed the moderating effect of personality disorder on psychodynamic and non-psychodynamic psychotherapy outcome. METHOD: Forty-nine subjects with primary DSM-IV panic disorder were randomly assigned to 12 weeks of twice-weekly Panic-Focused Psychodynamic Psychotherapy or Applied Relaxation Training. The primary outcome measure was the Panic Disorder Severity Scale; the moderating effect of Axis II psychopathology on the Sheehan Disability Scale was also tested. The trial was conducted between February 2000 and January 2005. RESULTS: Twenty-four subjects (49%) met DSM-IV criteria for a Structured Clinical Interview for DSM-IV Axis II Disorders-diagnosed personality disorder, of whom 19 (79%) had a cluster C diagnosis. Presence of a cluster C diagnosis moderated treatment outcome. Such subjects experienced greater improvements in Panic-Focused Psychodynamic Psychotherapy than subjects without cluster C comorbidity. CONCLUSIONS: Despite its small sample size, this exploratory analysis provides initial preliminary evidence corroborating the APA practice guideline recommendation. Future panic disorder clinical trials should explore Axis II moderator effects. CLINICAL TRIALS REGISTRATION: ClinicalTrials.gov identifier NCT00128388.
机译：目的：针对惊恐症的美国精神病学协会（APA）实践指南建议对患有合并症人格障碍的惊恐症患者进行心理动力学心理治疗。此建议无数据依据。这项探索性研究评估了人格障碍对心理动力和非心理动力心理治疗结果的调节作用。方法：将四十九名患有原发性DSM-IV恐慌症的受试者随机分为12周，每周两次，两次以恐慌为重点的心理动力心理疗法或应用放松训练。主要结局指标为恐慌症严重程度量表;还测试了Axis II精神病理学对Sheehan残疾量表的调节作用。该试验在2000年2月至2005年1月之间进行。结果：二十四名受试者（49％）符合DSM-IV的结构性临床访谈的DSM-IV轴II障碍诊断型人格障碍标准，其中19名（79％）进行了群集C诊断。群集C诊断的存在可缓和治疗效果。与没有簇C合并症的受试者相比，这类受试者在惊慌的心理动力心理治疗中获得了更大的进步。结论：尽管样本量较小，但该探索性分析提供了初步的初步证据，佐证了APA实践指南的建议。未来的恐慌症临床试验应探讨Axis II调节剂的作用。临床试验注册：ClinicalTrials.gov标识符NCT00128388。

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